Not exact matches
Another issue is that mucus is essential for immunity at epithelial surfaces, and glycosylation is essential for the
integrity of
cellular junctions and tissue barriers such as the
intestinal and blood - brain barriers.
Four out of ten users of NSAIDs experience symptoms such as heartburn, acid reflux, stomach burning, nausea, or bloating.56 Researchers have used NSAIDs to produce food intolerances in mice that result in a form of severe
intestinal damage called villous atrophy that is usually associated with celiac disease, 57 suggesting that a deficiency of arachidonic acid or the PGE2 made from it may underlie celiac disease and other food intolerances, perhaps by preventing the gut from forming
cellular junctions and thus impairing its
integrity.
Depression, associated with compromised
integrity of this
intestinal barrier, becomes the swirling storm of inflammation, impairment of
cellular machinery (i.e. mitochondria), oxidative stress, and inflammation in a carousel - like forward rotation.