Sentences with phrase «intestinal small cell»

This is most commonly used in intestinal small cell lymphoma.

Not exact matches

EGF, TGF - alpha, and human milk stimulate fetal small intestinal cell proliferation in vitro, with the greatest increase in cell proliferation seen following exposure to human milk.

Aging in intestinal stem cells leads to changes in villi, the finger - shaped protuberances that line the small intestine and absorb nutrients, and crypts, the valleys between villi where the intestinal stem cells live.

«Because the primary Small Intestine Chip recapitulates the physical microenvironment that cells experience inside the human body, such as fluid flow and cyclic peristalsis - like stretching motions, it exhibits a genome - wide gene expression profile that comes closer to its in vivo counterpart than that of the same intestinal cells grown as 3D organoids,» said first - author Magdalena Kasendra, Ph.D., a former Postdoctoral Fellow on Ingber's team and now Principal Scientist at Emulate, Inc. in Boston.

A goblet cell is a type of secretory cell found in the epithelium of the respiratory, intestinal (scattered among the absorptive cells of the small intestine and colon), and reproductive tracts.

Leveraging these technologies, the team generated expression profiles for a total of 53,193 small intestinal epithelial cells.

In contrast to embryos, lipid - containing structures in intestinal and epidermal cells of adult W01A8.1 null mutants (Figs. 5J and 5L) were smaller than lipid - containing structures in control animals (Figs. 5I and 5K).

A single - cell survey of the small intestinal epithelium.

When fluid is pumped slowly across both sides of the membrane, replicating the flow of liquid along the inside and outside of intestinal tissue in the body, the seeded cells not only differentiate into the four types found in the small intestine, but form tissue that spontaneously folds, develops villi, secretes mucus and even supports microbes commonly found in the small intestine.

The team then selected cells from these organoids and placed them inside the Intestine - Chips, which are about the size of AA batteries and re-create the natural microenvironment of the human intestine, including the intestinal epithelium — the layer of cells that forms the lining of both the small and large intestines.

Here we describe a method for fabricating a primary human Small Intestine - on - a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies.

Mesenchymal Stem Cell Seeding of Porcine Small Intestinal Submucosal Extracellular Matrix for Cardiovascular Applications.

The intestinal organoids that grew from these elements developed several of the singular characteristics of that tissue type, including small knobby protrusions (crypts) that in full - size intestines serve as receptacles for stem cells.

Daughters of the small intestinal stem cells, the Paneth cells, serve as crypt niche cells by providing Wnt, Notch and EGF signals (30).

Dr. Hackam's team has developed techniques of intestinal stem cell isolation and culture, and are working with tissue engineers and chemists towards the development of an artificial intestine, which has been tested in large and small pre-clinical models.

The condition is autoimmune in nature, which means gluten doesn't cause the damage directly; instead, your immune system's reaction to the gluten protein spurs your white blood cells to mistakenly attack your small intestinal lining.

Zinc deficiency causes leakiness in tight junctional seals and consequently epithelial cell layers of the small intestinal lining.

The intestines, especially the small intestine, allow only those substances to enter the body since the cells that contribute to the intestinal wall are tightly packed together.

It is my hypothesis that real foods have an inherent quality to them that allows the body to regulate it's immune function, build healthy red blood cells full of oxygen, restore proper balance to the flora of the intestinal microbiome, regenerating tight junctions to the wall of the small intestine.

In your intestinal tract, there reside very small micro-villi (thee are very tiny finger like projections which come off the lining of the intestinal tract with hair like cell membrane extensions — called the «brush border»), which serve as the major point of absorption of nutrients.

As the intestinal lining of the small bowel becomes more damaged over time, substances larger than particle size such as disease causing bacteria and fungus, potentially toxic molecules and undigested food particles pass through these weakened and «leaky» cell membranes.

In the study, sulforaphane prevented damage to the cells that line the small intestine, which can lead to intestinal ulcers and infections.

The small intestinal cells manufacture the very first lipoprotein particles that newly ingested fats will circulate within, called chylomicrons.

In the small intestine, gluten triggers the release of zonulin, a protein that regulates the tight junctions between epithelial cells and therefore intestinal, but also blood - brain barrier function.

Digestive enzymes are diverse and are found in the saliva secreted by the salivary glands, in the stomach secreted by cells lining the stomach, in the pancreatic juice secreted by pancreatic exocrine cells, and in the intestinal (small and large) secretions, or as part of the lining of the gastrointestinal tract.

With bitters, digestive enzyme secretions are increased, helping to promote the complete breakdown of nutrients into their absorbable units, preventing gas formation when large molecules are acted upon by bacteria further down the small intestine.2, 11 The complete breakdown of proteins is particularly important, as the cross reactivity of immune cells between undigested protein molecules and intestinal cells plays an important role in the etiology of conditions such as celiac disease.15 Insulin and glucagon secretions are stimulated, helping to stabilize blood sugar levels.3, 11 Many bitters formulations have been traditionally used in the treatment of type 2 diabetes, and it is interesting to point out that many naturally sweet substances are often paired with some bitterness in nature.4, 11 Herbalist Jim McDonald hypothesizes that our cravings for sweetness may mask cravings for bitterness for this reason.4

The study was done using an in vitro (i.e. «in glass» or test - tube) cell culture model of the small intestinal epithelium.

Intestinal epithelial cell proliferation is dependent on the site of massive small bowel resection

The body's own immune system attacks the cells that line the small intestine, resulting in the characteristic shortening or pruning of the intestinal villi (microscopic, finger - like projections of small intestine wall tissue made of columns of gut epithelial cells).

When small snippets of tissue from your cat's intestinal lining are sent to a pathologist, he / she can see if the typical cells and inflamatory response of IBD are present.

(Small cell lymphoma is found in the intestinal tract of cats, and is different than large cell lymphoma in that it has a slower progression.

When long - chain fatty acids are consumed, they are digested and absorbed into the small - intestinal epithelial cells; however, they are not transported directly into the blood supply but rather enter the lymphatics first.

INFLAMMATORY BOWEL DISEASE (IBD) The inflammatory bowel diseases (IBD) are the most common causes of chronic vomiting and diarrhea in dogs, and refer to a group of idiopathic, chronic gastrointestinal tract disorders, characterized by infiltration of the lamina propria by lymphocytes, plasma cells, eosinophils, macrophages, neutrophils, or combinations of these cells.12 The diagnosis of IBD requires the comprehensive exclusion of potential causes of gastrointestinal inflammation, including intestinal parasites, small intestinal bacterial overgrowth, bacterial enterocolitis, dietary intolerances or allergies, and neoplasia.12 Failure to eliminate known causes of gastrointestinal inflammation which can mimic IBD can result in frustration for the owner and clinician due to poor responsiveness of the animal to dietary or pharmacologic therapy.

Low - grade small cell lymphoma of the intestinal tract in cats is a less aggressive form of lymphoma.

I have two elderly rescue cats, one of whom has small cell intestinal cancer, the other enteritis.

Once a Giardia cyst is ingested by a dog, it makes its way to the dog's small intestine, where it opens up and releases the active form of the parasite which attaches itself to the intestinal wall and begins to reproduce by cell division.

Coccidia and Giardia are both small protozoans (one - celled organisms, NOT worms) that live in the intestinal tracts of dogs and cats.

Once the oocysts reach the small intestine, they release the organisms into the gut, where they embed themselves into the cells lining the intestinal wall.