Sentences with phrase «into human chromosome»

Many researchers and health officials worry that foreign DNA in a vaccine might slip into human chromosomes and interfere with their function.

A drug that stops the HIV virus from stitching itself into human chromosomes is found to fight AIDS in an animal study.

The more powerful one occurred within a stretch of DNA, or locus, that contains the HCP5 gene, which codes for a human endogenous retrovirus — a genetic fossil of a virus that wove itself into human chromosomes long ago but no longer produces infectious progeny.

Not exact matches

The analysis revealed that the human genome is organized into large pieces of low or high epigenetic stochasticity, and that these regions correspond to areas of chromosomes that are structurally different in the cell nucleus.

This new insight into how chromosomes are disassembled and reassembled during cell division will allow researchers to begin answering basic questions about epigenetic inheritance, as well as human disease such as chromosome disorders and cancer.

Rodríguez - Perales, Torres and Ramírez have shown that by transferring the RGEN components into primary human cells, regions of the exchanged chromosomes in some tumours can be marked, thus generating cuts in those chromosomes.

In this study, researchers took cells from patients with blood cancer MDS and turned them into stem cells to study the deletions of human chromosome 7 often associated with this disease.

As when he worked on the human genome, Venter is relying on a radical technique called shotgun sequencing: He chops up vast amounts of DNA into tiny pieces and then uses sophisticated computer analyzers to piece them back together into intelligible genes and chromosomes.

Most gene - therapy trials use viruses to deliver genes to a patient's cells, and most of those viruses are retroviruses, which have the ability to neatly splice their genes — and the human gene they're carrying — into a cell's chromosomes.

The mouse genome is sometimes described as the human genome chopped into 150 pieces and put back in a different order along the mouse's 21 chromosomes.

Not only could their new construction, dubbed «Sleeping Beauty,» slip into chromosomes, but a small test gene spliced into the transposon was also imported into the DNA of fish and human cells.

Most detailed analysis yet of Y chromosomes reveals how rapidly humans split into three groups in Arabia after emerging from Africa

The first step was to insert an artificial chromosome containing the cumbersome human antibody gene into the nucleus of a cow cell.

In today's Cell, researchers report that the DNA on the end of human and mouse chromosomes forms a loop, with the exposed end tucked back into the DNA strand.

Other Chinese groups had previously reported editing human embryos that could not develop into a baby because they carried extra chromosomes, but this is the first report involving viable embryos (SN Online: 4/8/16; SN Online: 4/23/15).

They knew the human genome was carved into 23 pairs of structures, called chromosomes, made from deoxyribonucleic acid, or DNA.

The team used ChromEMT to image and measure chromatin in resting human cells and during cell division (mitosis) when DNA is compacted into its most dense form — the 23 pairs of mitotic chromosomes that are the iconic image of the human genome.

Instead, human DNA is tightly wrapped into 23 structures called chromosomes to pack it more tightly and fit it inside a cell.]

The condition is more common than muscular dystrophy and cystic fibrosis, but the development of new therapeutic concepts is hindered by the fact that unlike muscular dystrophy and cystic fibrosis, where a single mutated gene causing the disease is known, the entire human chromosome 21 (containing around 300 genes) still has to be dissected into individual gene - dose contributions to the DS symptoms.

In truth, human chromosomes are tightly organized and packed into the nucleus, a situation which causes physical interaction between regions that might be hundreds of kilobases apart.

In my blog post about mitosis (http://www.myscizzle.com/phases-of-mitosis/), I explained some of the challenges a human cell faces when it tries to disentangle its previously replicated chromosomes (for an overview of the cell cycle, see also http://www.myscizzle.com/cell-cycle-introduction/) and segregate them in a highly ordered fashion into the newly forming daughter cells.

Studies of Y - chromosome diversity in other great apes are relatively undeveloped compared to those in humans, but have nevertheless provided insights into speciation, dispersal, and mating patterns.