Sentences with phrase «into airway cells»

Not exact matches

Flu vaccines are designed to prevent infection by eliciting antibodies against HA, which the virus uses to break into cells lining the airways.

Top series: Images show the elongated shape of cells transforming into a ball shape before they shed from the lining of the airway to cause obstruction, a key reason why RSV leads to bronchiolitis.

They found that infection of the narrowest airways of the lung by PIV3 alone caused moderate levels of inflammation, but after infection by PIV3 expressing RSV NS2, the epithelial cells lining the narrow airways were shed rapidly into the airway lumen.

«But what we've now shown is that RSV has an increased ability to cause airway obstruction because, during an RSV infection, the virus expresses a specific RSV - encoded non-structural protein, or NS2, in epithelial cells, causing the cells to shed from the airway lining and into the airway lumen.

By turning the pathway off, she guided the immature lung cells into becoming airway cells.

Thwarting this shedding effect wouldn't stop infection or stifle the typical symptoms of RSV infection, but it might limit the virus's ability to spread into the tiniest airways, which are the most likely to be obstructed by cells shed during infection.

The research team then tested RMC - 1 in cultured human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).

The cellular model of the airway mucosa could provide insight into biological and pathophysiological effects that conventional cell cultures or animal models do not capture, and help lead to the development of new therapeutics.

Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients.

Once produced, NO is freely diffusible and enters target cells and into the airway and can be detected in exhaled breath of all humans.