Sentences with phrase «into amyloid fibrils»

Mcc is a small — molecular - weight bacteriotoxin, with activity regulated in vivo by aggregation into amyloid fibrils at the stationary phase of the bacterial culture (Bieler et al., 2005; Shahnawaz et al., 2017).

«These findings suggest that the ability of proteins to aggregate into amyloid fibrils can be considered a more general property of proteins than previously believed,» says Massimo Stefani, a protein chemist at the University of Florence in Italy who co-led the project.

Instead of misfolding the healthy prion protein, PrP, into amyloid fibrils, which have been linked to disease, the team combined the PrP with various blends of lipids — fatty molecules believed to misfold it in the cell.

Not exact matches

Co-lead researcher, Australian National University Professor John Carver, said that two unrelated proteins aggregate in UHT milk over a period of months to form clusters called amyloid fibrils, which cause the milk to transform from a liquid into a gel.

But researchers in Italy and the United Kingdom reported in April that many different types of normal proteins — with no known link to diseases — can also fold into shapes indistinguishable from the dreaded amyloid fibrils.