Sentences with phrase «into bacterial genes»

So in the new study the researchers slipped the «alien» pair of bases into bacterial genes that also contained traditional bases.
They did so by inserting mutations into the bacterial gene that codes for the enzyme, then subsequently selecting mutants that were particularly effective at clipping off the antigens.

Not exact matches

The animals were five times as likely as regular mice to go into shock and die when exposed to bacterial cells, the group reports in the November 15 issue of Genes and Development.
Three options are on the table: tweak cereals so that they form symbiotic partnerships with rhizobia as legumes do; colonise cereal roots with other types of nitrogen - fixing bacteria; or transfer the bacterial genes that make fertiliser directly into the crop plants.
A plasmid, a simple kind of DNA - delivery vehicle, will move a gene for antibiotic resistance into the bacterial cells, jump - starting the Crispr - Cas9 system.
After just a single dose, rat intestinal cells pumped out bacterial lactase for up to 6 months — showing that the gut cells had inserted the gene into their DNA and were using it to manufacture the enzyme.
Bacteria expressing enzyme in one cell (bright green), while genetically identical cells do not, remaining protected from antibiotic onslaught; image courtesy of Yuichi Wakamoto / Neeraj Dhar / John McKinney Some strains of nasty bacterial infections, such as MRSA (methicillin - resistant Staphylococcus aureus), come loaded with resistance to antibiotics built right into their genes.
To supply lactase over the long haul, Matthew During and his colleagues at Jefferson Medical College in Philadelphia devised a strategy for incorporating the bacterial lactase gene into intestinal cells.
B: Well, we were in the midst of experiments aiming to use an animal virus to introduce new genes into human cells and into bacterial cells.
A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep - vein thrombosis — the formation of a harmful clot in a deep vein.
The team cut and pasted a bovine gene for NRAMP1, a protein linked to resistance against TB and other bacterial infections, into fetal dairy cow genomes.
Beginning in the 1970s, cloning techniques enabled researchers to create multiple copies of a gene by inserting it into a bacterial colony.
They then determined that those vital genes work together to transport a nutrient into the bacterial cell and chop up the nutrient so it can be used as food.
«We want to dig into this further and figure out how these ions impact bacterial gene expression, but that work is still underway.»
The islands are now free to move into other bacterial cells, bringing with them new sets of genes.
But people often reject ideas which don't fit into the bacterial model of gene regulation, which is that genes are turned on and off by proteins binding to DNA.
But Sauer fears that some companies, including those making industrial enzymes using natural bacterial genes spliced into E. coli, may find that their intellectual property has suddenly become worthless.
Based on bacterial genes, the team identified a human protein, selenium binding protein 1, which can convert methanethiol into other and compounds.
Bacteria share DNA with other organisms with which they come into contact, so an antibiotic - resistant gene can transfer from one type of bacterium to another, and a bacterial cell can become resistant to numerous antibiotics at once.
The new method circumvents the problem of not being able to culture many of these bacteria in the lab by transferring genes from these bacteria into another bacterial species that is easier to work with.
In one of the most elaborate feats of synthetic biology to date, a research team has engineered yeast with a medley of plant, bacterial, and rodent genes to turn sugar into thebaine, the key opiate precursor to morphine and other powerful painkilling drugs that have been harvested for thousands of years from poppy plants.
They injected DNA coding for a bacterial phytase gene into more than 4000 pig embryos, 1 % of which incorporated the gene.
Last April his team reported that they had pieced together bacterial, yeast, and wormwood genes and converted yeast into a chemical factory, yielding artemisinic acid.
These mutations are inserted into batches of yeast or bacterial cells, which express the altered gene and produce millions of random protein variants.
One could incorporate a metagenomic plasmid library into a probiotic strain and introduce the strain into a complex host — bacterial community to isolate genes that increase the strain's fitness in vivo.
Phage elements, including those not integrated into chromosomes, are part of a bacterial system for regulating genes.
For instance, some of these phage elements can activate or silence bacterial genes by moving into or out of the chromosome.
If a soil sample contains bacterial genes that produce enzymes used to convert carbon dioxide from the atmosphere into solid carbon, and these genes are active, researchers can conclude that microbes within the sample are actively storing carbon.
BAC stands for bacterial artificial chromosome, referring to the way the HD gene was put into the mouse.
The bacterial expression vector pGEX - 5 × -1 / Sp1 was constructed by introducing an EcoRI / XhoI — treated Sp1 gene fragment into EcoRI / XhoI — treated pGEX - 5 × -1 vector.
Phylogenomic analysis identifies evidence for lateral gene transfer of bacterial genes into the E. histolytica genome, the effects of which centre on expanding aspects of E. histolytica's metabolic repertoire.
Over the next few years genes from different bacterial (and eventually mammalian) species were cloned into plasmids and new cloning vectors such as pBR322, pACYC, and pUC were developed to provide higher copy number vectors that could be used in these cloning experiments.
Her game - changing technology takes a mysterious bacterial genetic code and transforms it into a powerful tool for cutting and pasting bits of genetic material — meaning not only could the entire field of gene therapy be revived, but her genome - editing tool could one day be used to treat a range of diseases, from cancer and AIDS to hereditary disorders like Down syndrome and Huntington disease.
A further approach is to introduce into the human body naked DNA — HIV genes that are sown into a circle of harmless bacterial DNA.
For example, a bacterial phytase gene has recently been inserted into yeast for commercial production.
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