Not exact matches
Last year, Robin Ali of University College London and colleagues demonstrated that immature retina cells from newborn
mice could form rod cells — a type of light - gathering cell — that wire
into the retinas of night -
blind adult
mice (SN: 5/19/12, p. 13).
Photoswitches inserted
into retinal ganglion cells (RGC) of
blind mice produce much less variety of response (all evenly red means the cells fire at the same time), while
blind mice with photoswitches inserted
into bipolar cells (ON - BC driven) exhibit much more variety in their retinal response to light, closer to that of normal
mice.
«This turned
into a nice story of long - term restoration of vision in completely
blind mice,» said Buck faculty and senior author Deepak Lamba, PhD, MBBS.
The team transplanted stem cell - derived photoreceptors
into another strain of
mouse, called CRX null, which is congenitally
blind.