Sentences with phrase «into brain cells in»

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.
«We're looking at bacteria that make magnetic nanoparticles, so we can insert their genes into brain cells in the same way,» Pralle says.

Not exact matches

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.
Any form of hurrying you into the birth process or, once into it, hurrying the process faster than it goes naturally will damage cells in the baby's brain.
The cells from baby are in Mom's brain and the cells from Mom cross into baby through her placenta.
Stem cells have also been identified in human milk, and have the potential to differentiate into mammary epithelial lineages under mammary differentiation conditions in vitro, as well as other cell types in corresponding microenvironments, including bone cells, brain cells, liver cells, pancreatic beta cells and heart cells.
Docosahexaenoic acid is incorporated in large amounts into cell membranes of the developing retina and brain.
She demonstrated that early experience leads to lasting changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer cells into healthy brain tissue.
In the direct reprogramming, the researchers exposed the adult skin cells to a specific mix of signaling molecules the scientists» past research had found would convert healthy skin cells directly into a type of brain cell called medium spiny neurons, without intermediate steps along the way.
Another gene, PCDH15, plays a role in the hair cells» ability to convert sound into brain signals (Molecular Psychiatry, DOI: 10.1038 / MP.2014.8).
Crayfish have a «nursery» in their heads where blood cells transform into neurons — the process may one day help us to regenerate our own brain cells
As the cochlea's fluid moves, about 15,000 hair cells sitting in it, each tuned to a particular frequency, pick up the motions; the cochlear nerve translates the movements into auditory messages that are sent to the brain.
When injected into mice engineered with a tau mutation that makes the protein clump abnormally in brain cells, triggering memory and motor problems, the antibodies reduced the clumping and improved the animals» behavior.
Scores of laboratories at universities and in private industry are uncovering how to use these cells, which transform into neurons, astrocytes (the cells that regulate transmission of electrical impulses in the brain) and oligodendrocytes (which insulate nerve fibers with a fatty coating).
In the past decade, a handful of discoveries have unleashed a flood of research into ways neural stem cells can be used for treating degenerative brain disorders and for brain repair.
The lack of these genes in the neurons of active mice suggested that their brain cells did not immediately leap into an excited state in response to the stressor.
When the researchers tracked the stem cells in the mice's brains, they saw that only about 5 percent of them actually developed into neurons, suggesting the cells did not rescue memory by replacing dead neurons, LaFerla says.
Soon after lung cancer cells (in green) spread into the brain, extracellular matrix molecules (in red) can shield them from the hostile surroundings.
In a separate but related study, scientists this week also announced that they successfully reversed Parkinson - like symptoms in several monkeys by transplanting human neural stem cells into their brainIn a separate but related study, scientists this week also announced that they successfully reversed Parkinson - like symptoms in several monkeys by transplanting human neural stem cells into their brainin several monkeys by transplanting human neural stem cells into their brains.
«We now know much more about how the cells work and how they best become integrated into the circuits in the brain
Published in the February 27 issue of Cell, the study found that tumor cells that reach the brain — and successfully grow into new tumors — hug capillaries and express specific proteins that overcome the brain's natural defense against metastatic invasion.
But scientists are making progress in refining these therapies, and the first ever trial of fetal stem cells injected directly into the brain is currently under way in children with Batten disease, a rare and fatal illness of the nervous system.
The cells, taken from the brain via the nose, have been coaxed into becoming insulin factories in the rat pancreas
The new findings prove that a group of cells in the brain can turn a short - lived sensation into complex, long - lasting muscle movements, says physiologist Simon Alford of Northwestern University.
The first step in the process involves inserting into those brain cells a gene that makes a light - sensitive protein.
«For these cell - level «rules» to be translated into specific brain proportions, we would also expect to see these rules reflected in predictable growth patterns of the mammalian brain, particularly in species from the same group of mammals,» she said.
The researchers tinkered with the voltage in cell membranes of developing African clawed frogs (Xenopus laevis) and found that electric charge plays a role in how big the brain grows and what kind of tissue developing cells grow into.
In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cellIn this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cellin key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.
In newborn mammals, the SVZ is the biggest depot for the precursor cells that migrate to populate various brain regions, and differentiate into multiple cell types.
«Disturbances to these processes may cause neuronal stem cells to develop into different types of cells or may cause neurons to migrate to different locations in the brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»
Nevertheless,» [the] study is very important because it demonstrates for the first time that we can use gene therapy to transform cells in the brain into ones that will secrete GDNF,» says Jeffrey Kordower, a professor of neurological sciences at Rush Presbyterian Medical Center in Chicago.
In one such approach, researchers surgically remove brain cells, use viruses to transfer genes to the cells, and then graft them back into the animal's brain tissue.
The team used human embryonic stem cells — which can transform into any cell of the body — and cultured them in a mixture of chemicals to grow human brain cells.
In the Cell Stem Cell study, Zhiheng Xu of the Chinese Academy of Sciences in Beijing sidestepped the mice's natural resistance to Zika virus by injecting a Samoan isolate directly into fetal brainIn the Cell Stem Cell study, Zhiheng Xu of the Chinese Academy of Sciences in Beijing sidestepped the mice's natural resistance to Zika virus by injecting a Samoan isolate directly into fetal brainin Beijing sidestepped the mice's natural resistance to Zika virus by injecting a Samoan isolate directly into fetal brains.
In «Diabetic rats cured with their own stem cells ``, we report how researchers cured diabetic rats by turning brain stem cells extracted through the nose into insulin - producing cells in the pancreaIn «Diabetic rats cured with their own stem cells ``, we report how researchers cured diabetic rats by turning brain stem cells extracted through the nose into insulin - producing cells in the pancreain the pancreas.
In the depths of the mind, networks of brain cells perform a sublime symphony, and a twinkle of insight pops into consciousness.
The cells that make up the walls of blood capillaries are joined together more tightly in the brain than elsewhere in the body, preventing proteins and cells getting into the brain.
A subset of the implanted human stem cells matured into rotund, humanlike astrocytes in the animals» brains, taking over operations from the native mouse astrocytes.
Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.
The brain is protected by a barrier of cells that tightly regulates the transport of substances into this organ in order to prevent infection.
A group of really brainy scientists have moved closer to growing «therapeutic» brain cells in the laboratory that can be re-integrated back into patients» brains to treat a wide range of neurological conditions.
Affecting the central nervous system, it causes neonatal meningitis by multiplying in immune cells, such as macrophages, and then disseminating into the bloodstream to subsequently invade the blood - brain barrier.
However, occasionally germ cells can get trapped in the wrong part of the body during development and may later turn into brain tumours, for example.
According to tradition in neuroscience, brain cells fall into two broad groups — neurons and glial cells.
The recipe, described in Nature, allows human pluripotent stem cells to spontaneously attempt to assemble into a tiny approximation of a whole brain by making whatever brain structures the stem cells choose.
In the present study, her team took skin cells from patients with lissencephaly and turned them into iPS cells, which they then cultivated under special conditions into neuronal stem cells and neurons that are copies of those in the patients» brainIn the present study, her team took skin cells from patients with lissencephaly and turned them into iPS cells, which they then cultivated under special conditions into neuronal stem cells and neurons that are copies of those in the patients» brainin the patients» brains.
A 2010 study in Stem Cells and Development showed that fetal cells can migrate to the brain of a mother mouse and mature into neurons, Nelson Cells and Development showed that fetal cells can migrate to the brain of a mother mouse and mature into neurons, Nelson cells can migrate to the brain of a mother mouse and mature into neurons, Nelson says.
We not only introduced the gene into specific brain regions of the mouse, but we could also direct it to specific cell types to test which ones played a role in regulating sociability.»
These rare, damage - repairing cells are found in many organs (including the brain), but the cells can transform into only a limited range of cell types.
According to his unpublished findings, when he puts glioblastoma cells from patients into lab dishes with brain organoids, the cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened in the patient's own brain,» Fine said.
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