Sentences with phrase «into brain cells using»

The scientists collected skin cells from 19 people, aged from birth to 89, and prompted them to turn into brain cells using both the induced pluripotent stem cell technique and the direct conversion approach.

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Whenever a sweet substance touches the tongue, our brains senses that this is food and it is time for our body to produce insulin to take that food and bring it into our cells for the use of energy.

Scores of laboratories at universities and in private industry are uncovering how to use these cells, which transform into neurons, astrocytes (the cells that regulate transmission of electrical impulses in the brain) and oligodendrocytes (which insulate nerve fibers with a fatty coating).

In the past decade, a handful of discoveries have unleashed a flood of research into ways neural stem cells can be used for treating degenerative brain disorders and for brain repair.

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

Nevertheless,» [the] study is very important because it demonstrates for the first time that we can use gene therapy to transform cells in the brain into ones that will secrete GDNF,» says Jeffrey Kordower, a professor of neurological sciences at Rush Presbyterian Medical Center in Chicago.

In one such approach, researchers surgically remove brain cells, use viruses to transfer genes to the cells, and then graft them back into the animal's brain tissue.

The team used human embryonic stem cells — which can transform into any cell of the body — and cultured them in a mixture of chemicals to grow human brain cells.

For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.

Incoming sound waves make the eardrum vibrate, and the eardrum delivers these vibrations using the ossicles to the inner ear where hair cells translate them into electric signals sent to the brain.

«We putzed around and tried different things,» he said, and after some false starts — they weren't using quite the right brain - making ingredients, so the stem cells developed into micro-pancreases and colons — it worked.

Novitch's UCLA lab group has likewise used its brain organoids to pinpoint additional receptors by which the virus may gain entry into neural stem cells, and identified a few other drug leads for blocking infection.

To replicate these cell culture results, Rani used human stem cells to grow neurons into what is called a mini brain.

Earlier this year, Lerner, Xie and their colleagues reported using the new method to find an antibody that can perform the remarkable trick of turning bone marrow cells into young brain cells, via a previously unknown signaling mechanism.

Shenoy's lab pioneered the algorithms used to decode the complex volleys of electrical signals fired by nerve cells in the motor cortex, the brain's command center for movement, and convert them in real time into actions ordinarily executed by spinal cord and muscles.

Investigations into human brain development using human cells in the culture dish have so far been very limited: the cells in the dish grow flat, so they do not display any three - dimensional structure.

McKay announced that he had mitigated the symptoms of Parkinson's in rats by using mouse embryonic stem cells that he had turned into dopamine - producing brain cells.

An intracortical BCI uses a tiny silicon chip, just over one - sixth of an inch square, from which protrude 100 electrodes that penetrate the brain to about the thickness of a quarter and tap into the electrical activity of individual nerve cells in the motor cortex.

Using cutting edge «disease in a dish» technologies, the researchers are now following up the leads discovered in blood cell lines in neurons induced from stem cells derived from the blood of PMDD patients — in hopes of gaining a more direct window into the ESC / E (Z) complex's role in the brain.

Because stem cells have the ability to develop into many different cell types in the body, researchers at USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery & Brain Repair have focused on using stem cells to restore function lost through neurodegenerative disorders or injuries.

After measuring millivolt changes in 58 brain cells in frogs in response to sound, the researchers used a mathematical model to convert the information into how much a brain cell was excited or inhibited by a given sound pulse.

Both teams used viruses to insert four genes comprising the transcription factors into skin cells, and demonstrated that brain, heart and other tissues could be created from cells created this way.

The researchers injected a compound normally used to label tumor cell division into patients who had agreed to have their brains examined after death.

Using a miniature microscope inserted into the brains of the mice, Hen's team recorded the activity of hundreds of cells in the hippocampus as the mice freely moved around their surroundings.

Electric fields can be used to guide neural stem cells transplanted into the brain towards a specific location.

In a second test, Chen and his team used a transgenic - mouse model for Alzheimer's disease, and demonstrated that reactive glial cells in the mouse's diseased brain also can be converted into functional neurons.

He said he used techniques to differentiate pluripotent stem cells into cells that are designed to become neural tissue, components of the central nervous system or other brain regions.

The rabies virus, transmitted largely through the bites of infected animals, has evolved over thousands of years to hijack nerve cells, which it uses to climb from infected muscle tissue into the brain.

Hair cells in the cochlea use this gradient to convert the mechanical force of the vibrating eardrum into electrical signals that the brain can understand.

Electric fields can be used to guide neural stem cells transplanted into the brain toward a specific location.

Using a miniature microscope inserted into the brains of the mice, the researchers recorded the activity of hundreds of cells in the hippocampus as the mice freely moved around their surroundings.

Gladstone scientist Dr. Sheng Ding has exposed more chameleon - like qualities of the human skin cell, using chemical cocktails to turn skin cells into fully functional brain, heart, liver, and insulin - producing pancreas cells.

Recently, Dr. Ding achieved entirely gene - free chemical reprogramming, using only drugs to turn fibroblasts directly into brain cells.

Using unique drug cocktails, stem cell scientist Sheng Ding, PhD, a senior investigator at the Gladstone Institutes, can transform fibroblasts (skin cells) into fully functional brain, heart, liver, and insulin - producing pancreas cells.

The advantages of this approach began to emerge in 2011, when Dr. Ding announced that he had used his «chemical reprogramming» method to convert human skin cells into brain cells.

Neurons - the brain cells that use electricity to do thinking stuff - are really hard to turn into a treatment.

Stem cell scientist Sheng Ding has used his unique drug cocktails to turn skin cells into brain, heart, liver, and insulin - producing pancreas cells.

The technique used in the study — optical stimulation of brain cells, or «optogenetics» — involves the insertion of a gene into parts of a brain to make them sensitive to blue light and then stimulating them with the light.

In addition to the normal tools of the cell biologist's trade, Simona's lab uses intravital imaging to peer into the brains of mice.

SAN FRANCISCO, CA — In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.

Grants are to be used for innovative and transformative research into the detailed cell biology of the brain.

Thus, for the specific example you gave of using autologous bone marrow stem cells injected into the brain, this scenario would indeed require full FDA approval as it does not meet the criteria of homologous use, as you said.

Some cells differentiated themselves into various types of the nerve cells (neurons) found in several brain regions, while others remained «neural progenitors,» creating a reservoir of potential neurons to be used later.

In a major breakthrough, Gladstone scientists transformed skin cells into heart cells and brain cells using a combination of chemicals and without adding external genes to the cells.

In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.

Human skin cells have also been directly converted into neurons that can be used to study and find treatments for diseases in the brain, as well as liver cells and insulin - producing cells of the pancreas.

In two studies published in Science and Cell Stem Cell, the team of scientists, who were led by Gladstone senior investigator Sheng Ding, PhD, and are part of the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain ceCell Stem Cell, the team of scientists, who were led by Gladstone senior investigator Sheng Ding, PhD, and are part of the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain ceCell, the team of scientists, who were led by Gladstone senior investigator Sheng Ding, PhD, and are part of the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain ceCell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain cecell - like cells and, ultimately, into heart or brain cells.

In a revolutionary set of studies, Gladstone scientists pioneered a way to reprogram skin cells into heart cells and brain cells using only a combination of chemicals and without adding any external genes to the cells.

«Our approach could lead to a simpler method of creating iPSCs or could be used to directly reprogram skin cells into other cell types, such as heart cells or brain cells.»

She has explored this theory using «tracer» molecules that follow the paths of brain cells to see how one brain area connects to another, watching as the medial preoptic area extends into the song control areas.