High - throughput data acquisition streamlines complex experiments, while simple protocols for multiplexed analysis provide deeper insight
into cell behavior.
This insight
into cell behavior could help researchers better understand cell jamming and unjamming, which could lead to potential treatments for conditions such as developmental abnormalities, asthma, and cancer.
Not exact matches
Neurobiology is the study of
cells of the nervous system and the organization of these
cells into functional circuits that process information and mediate
behavior.
When injected
into mice engineered with a tau mutation that makes the protein clump abnormally in brain
cells, triggering memory and motor problems, the antibodies reduced the clumping and improved the animals»
behavior.
In cancer
cells, the protein networks that control the
behavior are changed in such a way as to cause the
cells to lose control and break away — a mutated skin
cell, for instance, might then migrate
into the bloodstream.
As Pardridge studied the protein more carefully, he realized that it transports essential insulin
into the
cell and then out the other side, from which point the hormone travels
into the brain to help regulate eating
behavior.
The distribution of fluorescent daughter
cells can be used to create a mathematical model of blood formation, which can provide new insights
into the
behavior of stem
cells.
Reichert says that such ultrathin layers of water are a common phenomenon, and understanding the
behavior of HDL and LDL water may lead to insights
into water's
behavior in diverse situations, from ice skating to ion movement across biological
cell walls.
And it's essential to understand how neurobiological processing conducted by molecules and
cells and electrical signaling gets translated
into behaviors, from simple bodily movements to complex social interactions.
Greber and his team infected human
cells in culture with the chemically labeled viruses, and observed the
behavior of the viral DNA during entry
into cells.
«This year's Nobel Laureates have been studying this fundamental problem and solved the mystery of how an inner clock in most of our
cells in our bodies can anticipate daily fluctuations between night and day to optimize our
behavior and physiology... since the paradigm shifting discoveries by Hall, Rosbash and Young, circadian biology has developed
into a highly dynamic research field with vast implications for our health and well - being.»
In a study spanning molecular genetics, stem
cells and the sciences of both brain and
behavior, researchers at University of California San Diego, with colleagues at the Salk Institute of Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights
into the underlying neurobiology of the human social brain.
Learning about
cells» social interactions may give researchers new ways to peer pressure
cells into good
behavior.
They then tested the
behavior of human tumor
cells with and without HOXA5 by injecting those
cells into the mammary fat pad of mice.
When they put stem
cells into this viscoelastic microenvironment and tuned the rate at which the gel relaxed, they observed dramatic changes in the
behavior and differentiation of the
cells.
Second, the report recommends banning research that attempts to transplant enough human - derived neural
cells into a nonhuman primate to prompt human - like
behavior.
Exosomes are tiny packets of proteins, microRNA and nucleic acids that
cells emit
into their environment to both communicate with neighboring
cells and influence their
behavior.
The information gathered by your senses is transmitted by nerve
cells, or neurons, to specific brain regions where the signal is routed through circuits and sent downstream to areas that essentially translate the information
into behavior and get you back on track.
However, when forced to express the eye field transcription factor (EFTF) genes, the
cells differentiate
into all seven retinal
cell classes and eventually organize themselves
into a functioning eye that can detect light and guide tadpoles in a vision - based
behavior.
This research makes use of single - molecular fluorescence imaging technology to visualize and analyze the
behavior of exogenous DNA that were introduced
into the
cell from outside.
Often, their
behavior does not reflect their biological function within an entire organ or organism, which, for example, turns studying human liver
cells into a big challenge.
Using the spinal cord as a model, Jessell deciphered at the molecular level how different types of nerve
cells are generated, as well as the steps that drive their assembly
into the circuits mediating motor coordination and reflexive
behaviors.
Dec. 6, 2016 — A new microfluidic device containing human
cells that faithfully mimics the
behavior of the blood - brain barrier is providing new insights
into brain inflammation, the silent killer.
Core areas of research at the institute include work on brain - computer interfaces to aid patients with spinal injury and paralysis; innovative advances in computational neuroscience to address
behavior and mood disorders; and research
into mechanisms of
cell death as part of efforts to identify therapies for neurodegenerative diseases that include amyotrophic lateral sclerosis (ALS) and Alzheimer's.
Moreover, he said, «It's the first time we've really gained insight
into a particular
cell's and molecular pathway's roles in complex
behavior across such diverse species.»
An unusual collaboration between
cell and developmental biologists and physicists at UNC - Chapel Hill is providing insights
into the relationship between the physical properties of
cells and the signals that influence
cell behavior.