Sentences with phrase «into cell cycle»

Activated HGF interacts with c - met receptors of satellite cells, promoting their entrance into the cell cycle.

«Most adult mammalian beta cells are in a quiescent phase, and so if you want to push them into the cell cycle, you need to shake them out of their sleep,» explains Kulkarni, who is also a Professor of Medicine at Harvard Medical School.

Not exact matches

In this special section of Science, expert contributors retrace the long and tortuous path leading to the mapping and identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activity.

If it was, scientists could extrapolate a lot of what was known about the yeast cell cycle into the still - mysterious human cell cycle.

This maneuver «froze» the cells in a quiescent phase of their division cycle and may have made their chromosomes more susceptible to being reprogrammed to initiate the growth of a new organism after the nuclei were transferred into an egg.

He hopes to pursue projects such as developing therapeutics with chemists, working with biophysicists to study protein conformational changes relevant to viral entry into the cell, and investigating cellular trafficking pathways relevant to the viral life cycle in collaboration with cell biologists.

Two - way fuel cells Meanwhile, Versa, a solid oxide fuel cell stack supplier, is working with Boeing and «a large European company» on an innovative reversible SOFC that cycles back and forth between providing power and electrolyzing water into hydrogen and oxygen, Stokes says.

«Nematodes use the spit to transform the host cell into a nutrient sink from which they feed on during their entire life cycle.

Lee's study results, which appear in the July 16, 2015 issue of Nature Communications, revealed new understanding about how 14 -3-3 sigma — a cell cycle «controller» - regulates cancer metabolic programming, thus protecting healthy cells from turning into tumor - producing factories.

The CD4 cycle alone would be enough to kill a person, but HIV also enters other cells, integrating into their genomes as well.

«Our study found that by introducing an inhibitor of the STAT3 protein in repeated cycles, we could alternately replenish the pool of satellite cells and promote their differentiation into muscle fibers,» said Alessandra Sacco, Ph.D., assistant professor in the Development, Aging, and Regeneration Program at Sanford - Burnham.

Transferring the mutant B cells into mice, the researchers further showed that Foxo1 has a vital role in the cycling of B cells between light and dark zones.

Other studies have shown that the virus is capable of moving into brain cells, modifying the regulation of the cell cycle, and inducing their death.

«In modern biology mitochondria are considered to be much more than the powerhouse of the cell; they integrate multiple intracellular signals to regulate progression through the cell cycle and into apoptosis.

They inhibit viral infection by preventing viral entry into target cells and by blocking different stages of the viral replicative cycle for different viruses.

Once freed, the proteasome degrades proteins required for cell cycle progression, thus driving cells into senescence.

Progenitors of the central retina are the first to leave the cell cycle and differentiate into the six neuronal and one glial cell class of the mature retina.

It is currently suggested that HCECs are held in the G1 phase of the cell cycle and can not pass readily into the S phase prior to cell division [14].

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

This acquisition can be divided into several interdependent and sequential phases, from the time point when progenitor cells exit the cell cycle toward the newly formed and perfectly differentiated neuron.

Cells were collected from either the media (floating subpopulation) or the adherent subpopulation after each hypoxic cycle and dissociated into single - cell suspension by trypsin / EDTA (trypsin / ethylenediaminetetraacetic acid).

By growing primordial germ cells in culture researchers can make genome edits sequentially without being restricted by the breeding cycle of living birds, and the cultured cells will contribute to the germ line when injected into new embryos.

Manuscripts that increase our understanding of the processes through which stem cells and progenitors differentiate into committed progeny, the commitment cell death programs such as apoptosis and necrosis, aging, and the transition between proliferation and cell cycle arrest are welcome.

Single - cell transcriptomics on pluripotent stem cells has provided new insights into cellular variation, subpopulation structures and the interplay of cell cycle with pluripotency.

In my blog post about mitosis (http://www.myscizzle.com/phases-of-mitosis/), I explained some of the challenges a human cell faces when it tries to disentangle its previously replicated chromosomes (for an overview of the cell cycle, see also http://www.myscizzle.com/cell-cycle-introduction/) and segregate them in a highly ordered fashion into the newly forming daughter cells.

In the 1990s, researchers were beginning to understand the ways cells regulate transitions into the four phases of the cell cycle: G1, synthesis (S) phase, G2, and mitosis.

Finally, we show that inactivation of DNA damage checkpoint kinases in senescent cells can restore cell - cycle progression into S phase.

These commonly regulated genes clustered into the functional category of cell - cycle regulators.

Acetyl - CoA goes into the Krebs cycle where it is used to produce ATP to fuel the cells.

The body then tries to produce more insulin to get the sugar into the resistant cells, and a cycle begins.

[7] Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), [8] especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress.

Now insulin and leptin are not staying high for a few hours a day, but staying high throughout the entire day... and night, whether one eats or not... Causing more and more insulin and leptin resistance in a vicious cycle until, at least for insulin, the islet cells start burning out... lowering insulin but further raising glucose... and now we are into full - blown diabetes.

As the cycle progresses, glucose continues to build up in the body, leaking into the urine and drawing water from cells in the body into the urinary tract, leading to constant dehydration despite increased water intake.

As part of its life cycle, the fungus grows in the soil (saprophytic cycle) and matures, drying into fragile strands of cells.

Working on the PCV is important, many factors go into red blood cell production starting with a hormone secreted by the kidneys called erythropoietin (you hear about it a lot in sports like cycling) which stimulates red blood cell production; more investigation may be needed to determine if the problem is an increase in destruction or a decrease in production.

This kick starts other convection cells into full fledged thunder storms and the cycle continues for ever.

The Carbon Cycle Photosynthesis takes CO 2 out of the atmosphere Cell Respiration by all organisms puts CO 2 into the atmosphere Transfer.