Sentences with phrase «into cell nuclei»

Parkinson contends that targeted gene replacement produces cells having specific genetic alterations far more effectively than the traditional technique for making transgenic animals, which entails injecting DNA into cell nuclei.

Researchers at Cold Spring Harbor Laboratory in New York have discovered that a protein called Importin - 11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus.

The complex then migrates into the cell nucleus, and activates the transcription of specific target genes which are involved in physiological and pathological bone formation (Chen, Deng & Li, 2012; Katagiri & Tsukamoto, 2013; Miyazawa et al., 2002).

Not exact matches

They're hoping to find out what controls the size of the nucleus, the central compartment of a cell that contains the DNA, and other components of the cell as it develops into a many - celled organism.

Molecular biology, contrary to the article, does not support evolution by natural chance because evolution can not occur without inheritance, inheritance can not occur without DNA and DNA is so complex it could not have evolved by chance unless we are to assume that molecules just happened to arrange themselves into the DNA molecule at the same times as a nucleus formed to hold the DNA, at the same time as the cell membrane just happened to form around it, at the sametime as all the cell maintaining process in the cytoplasm just happened to come into existence to form a single cell and that all these aspects just happened to come together and work harmoniously.

Given the tension and consequent ambiguity built into the fabric of Whitehead's portrayal, it only extenuates the competing claims between organ / cells, cell / molecules, molecule / nuclei / electrons, and also crystal / atoms, metal / electrons, quarks / universe.

Then, the DNA would be removed from an oocyte (an egg cell) and this enucleated oocyte fused to the altered adult cell» creating a new cell that is neither an oocyte nor an adult cell but a hybrid exhibiting the properties programmed into it by the alterations made to the adult - cell nucleus.

Should the ANT - OAR proposal work, the alterations made to the adult nucleus will ensure that the cell produced by ANT - OAR enters immediately into a restricted, pluripotent state, without ever generating a totipotent embryo.

The cell nuclei are removed from both sets of embryonic cells, as shown in the diagram, the donor's nuclei and the remains of the parents» embryo are destroyed and the parents» nuclei are then inserted into the donor or «host» embryo, still containing its healthy mitochondria.

Cloning requires the insertion of a cell nucleus into a denucleated egg, and perfecting human SCNT techniques will require much trial and error, meaning a potential vertical spike in demand.

That question answered, Saïb started working on how foamy viruses move within cells to import their genome into the host cell's nucleus, which is what his adviser considers his most important work.

Many of the mutations in ASD, Yan explained, result from chromatin remodeling factors, which are involved in dynamically changing the structure of chromatin, the complex of genetic material in the cell nucleus that condenses into chromosomes.

In somatic cell nuclear transfer, a nucleus from a mature body cell is transplanted into an egg cell without a nucleus.

The analysis revealed that the human genome is organized into large pieces of low or high epigenetic stochasticity, and that these regions correspond to areas of chromosomes that are structurally different in the cell nucleus.

In the paper, published in the now - defunct online journal e-biomed, West, Lanza and their colleagues showed that they could pull a nucleus from a human egg cell, replace it with a whole adult ovarian cell and generate an embryo that divided into six cells.

For example, a protein in a cell might start life in the nucleus and then move into the cytoplasm to take part in cell signaling.

To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.

A few years ago, Snyder's team and other researchers found that if NO reacts with GAPDH, GAPDH can then bind to another protein that whisks GAPDH away from its humdrum sugar metabolism tasks and into the nucleus, the cell's control center.

Some of the proteins in the chloroplast are made from hereditary genes in the chloroplast itself, while other proteins (such as Sco2) are made from the DNA in the nucleus of the plant cell and then imported into the chloroplast.

Goats as Drug Factories Initially, GTC generated transgenic goats by microinjecting into the developing nucleus of a one - cell embryo a gene encoding the desired human protein (along with DNA that promotes activation of that gene in milk).

Using their nuclei to exert force, they insert themselves between — as well as into — the cells (called endothelial cells) in the vessel walls.

The modified cell nuclei were then inserted into unfertilized eggs to create engineered pig embryos, which were implanted in a normal sow.

And while cytochalasin D might not be the actual agent scientists use to trigger bone formation in the clinic, Rubin's study shows that triggering actin transport into the nuclei of cells may be a good way to force mesenchymal stem cells to become bone cells.

They have converted the nucleus at the middle of each cell into a light - collecting lens.

At an early stage of this process, BRDT enters the nucleus and switches on relevant parts of the genome that instruct the cell to mature into a sperm cell.

This maneuver «froze» the cells in a quiescent phase of their division cycle and may have made their chromosomes more susceptible to being reprogrammed to initiate the growth of a new organism after the nuclei were transferred into an egg.

At an early stage of this process, BRDT enters the cell nucleus and switches on the parts of the genome that instruct the cell to mature into a sperm cell.

In the initial work at the Roslin Institute, the egg cells along with their transplanted nuclei were then implanted directly into a foster mother, where they developed and, in the case of Dolly, resulted in a viable offspring.

The nuclei are inserted into egg cells which have had their original nucleus removed, a process called nuclear transfer.

Billions of years ago, an iron nucleus forged in another galaxy was flung into space at close to the speed of light — headed for your cells

Other researchers have previously cloned animals, including mammals, by transferring nuclei from embryonic cells into such enucleated eggs.

Axons can be very long and relatively remote from the central portion of the cell, which houses the nucleus where DNA is transcribed into messenger RNA that can then be converted into proteins.

Instead, Sen found that actin was trafficked into the nuclei of the stem cells, where it had the surprising effect of inducing the cells to become osteoblasts.

To create cloned mice, the team inserted nuclei from so - called cumulus cells, which surround the ovary, into egg cells, or oocytes, without nuclei.

In 1957, developmental biologists first discovered that they could insert the nucleus of adult frog cells into frog eggs and create dozens of genetically identical tadpoles.

With more - than -30-year-old frozen tissues from a preserved frog, the team extracted and implanted the nucleus of a dead cell into a fresh host egg from a distantly related species.

In the nucleus of eukaryotic cells, DNA is packaged with histone proteins into complexes known as chromatin, which are further compacted into chromosomes during cell division.

Before Katlyn showed up at NIH, the doctors there were already well prepared: They had inserted healthy human ADA genes into a modified mouse retrovirus — a type of virus that can enter human cells and transfer new genetic material right into the DNA strands in their nuclei.

Amoeba reproduction is an asexual event in which the organism doubles its genetic material, creates two nuclei and then sets about dividing into two cells.

The image shows human cells (green) on the nanoneedles (orange), which has DNA injected into the cells» nuclei (Blue).

The researchers show that cells of the same type take up different amounts of viral DNA into their nucleus.

The relatively short viral DNA strand then moves to the cell nucleus, where it inserts itself into the host cell's DNA.

If the researchers find cells with decent enough DNA, Iritani says, he would inject a mammoth cell's nucleus into an elephant egg and zap it with electricity to jolt the egg into fertilization mode.

An adult cell nucleus (upper right) is injected into a mouse egg that lacks genetic material.

RNA messages are copies of small snippets of DNA that move out of the cell nucleus to be converted into proteins.

Histone is a protein that acts like a spool for DNA, helping to package the six - foot long DNA strand into the tiny nucleus of every cell.

The patent gives California - based Geron Corp. exclusive rights to animal embryos prepared by transferring the nucleus of a quiescent diploid donor cell into a suitable recipient cell up to and including the blastocyst stage.

The scientists starved the cells into quiescence, then transferred their DNA - carrying nuclei into egg cells stripped of their own nuclei.

When they tracked the cells» axons from the eye into the brain, they saw that many of them terminated in the lateral geniculate nucleus (LGN), the first relay station in the brain for visual information.

Long dismissed as a mere messenger, RNA is perhaps best known for its role ferrying instructions from the genome, which is cloistered in the nucleus, to more far - flung parts of the cell, where it is made into protein.