So to generate autoimmunity against Neu5gc incorporated in human cells, B cells must first be triggered to form high - affinity anti-Neu5gc antibodies by meeting bacterial pathogens who have incorporated Neu5gc
into their cell walls.
To date, the published research on this topic has focused on the possibility of pathogens incorporating Neu5Ac, the primary human sialic acid, from human cells
into their cell walls, and subsequently triggering autoimmunity against Neu5Ac.
This can happen because some bacteria do incorporate sialic acids from their local environment
into their cell walls; and thus gut bacteria will incorporate Neu5Gc from food into cell walls.
There has been little study of the possibility that gut pathogens will incorporate Neu5Gc from food
into their cell walls, potentially triggering autoimmunity against Neu5Gc incorporated in human cells.
Replace the real thing with margarine or butter substitutes and the body will incorporate these inferior fats
into the cell walls instead.
Unlike plants and animals, bacteria need a small amount of D - amino acids, not to incorporate into proteins, but to incorporate
into cell walls to increase resistance and stability.
Nearly one year ago, with the help of a prison tailor shop instructor and a correction officer, Richard Matt and David Sweat cut
into their cell walls and into a steam pipe and crawled through it to emerge through a manhole on a street in the village of Dannemora.
Using many advanced techniques though, we saw that some very small, low - molecular - weight compounds were working their way
into the cell wall.
Not exact matches
Typically, the group consists of a «tie - down team» who escort the prisoner from his
cell to the death chamber and then strap him to the gurney; medically trained personnel who set the intravenous lines; and those, like Bracey and Baxley, who sit on the other side of a glass
wall and press the buttons to inject the lethal drugs
into the prisoner once the team leader gives the order.
Slow cooking breaks the
cell walls in the plant and animal ingredients, allowing a significant uptake of vitamins and minerals
into your body.
Autoimmunity is commonly caused by bacterial infections or overgrowth in the small intestine, in which partially digested food compounds are incorporated
into bacterial
cell walls and then the immune system, reacting to the bacteria, forms antibodies that also recognize food compounds, some of which might cross-react with human counterparts.
On the
walls of the lactocytes (milk - producing
cells of the alveoli) are prolactin receptor sites that allow the prolactin in the blood stream to move
into the lactocytes and stimulate the synthesis of breastmilk components.
Tattoos are permanent because the ink remains
walled off within the body via the body's inflammatory process, making the possibility of the ink migrating
into the mother's blood plasma and then
into the milk - making
cells of the breast, next to impossible.»
This rapidly dividing ball of
cells separates
into two sections: the inner group of
cells will become the embryo and the outer group of
cells will burrow
into the uterine
wall for nourishment.
Meanwhile, seven or eight days after a sperm fertilizes an egg in week 4 of pregnancy, a mass of
cells — the earliest form of an embryo — implants
into the
wall of the uterus.
Some
cells from this mass split away, burrowing deeper
into the uterine
wall.
There are receptors on the
walls of the alveoli's milk - producing
cells that allow prolactin to move
into the lactocytes and trigger the synthesis of breast milk.
In humans, however, it sparks a cascade of symptoms that begin when the bacterium injects a sort of syringe
into the
cells of the intestinal
wall.
Using their nuclei to exert force, they insert themselves between — as well as
into — the
cells (called endothelial
cells) in the vessel
walls.
Since the
cell wall is the target of most antibiotics, understanding how bacteria grow their
cell walls may provide insight
into more effective medicines.
When the protein is unfolded, tiny bubbles filled with neurotransmitters can stick to it, fuse to the inside
wall of a nerve
cell and then break free
into a synapse.
Reichert says that such ultrathin layers of water are a common phenomenon, and understanding the behavior of HDL and LDL water may lead to insights
into water's behavior in diverse situations, from ice skating to ion movement across biological
cell walls.
The
cells that make up the
walls of blood capillaries are joined together more tightly in the brain than elsewhere in the body, preventing proteins and
cells getting
into the brain.
The capsule protects the donator's
cells against attacks of the immune system but, passes the hormones by semi-permeable
walls into the body of the receiver.
In a step toward accelerating the production of new gene therapies, scientists report in ACS Nano that they have developed remote - controlled, needle - like nanospears capable of piercing membrane
walls and delivering DNA
into selected
cells.
They've even injected white blood
cells into the vessels and watched as they squeezed through gaps in the vessel
wall to reach the tissue on the other side, just as they do in the human body.
The thin
walls of the microvessels mean that the oxygen levels in adjacent brain tissue are mirrored within the capillaries, which can signal to red blood
cells to spring
into action.
One approach to tapping
into all that biomass focuses on cellulose, the material that gives plant
cells their strong
walls.
The fungus makes the chelator and produces hydrogen peroxide from oxygen, and together they start to digest the
cell wall into the sugar found in the basic building block of wood, glucose, which the fungus can use as food.
With the help of sensors, specialized
cells in the intestinal
wall determine which hormones, if any, should be released
into the bloodstream.
In a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel
walls, and
into almost every muscle
cell in the bodies of hamsters bred to have human genetic diseases.
Tenapanor works by inhibiting a molecule in
cells in the intestinal
wall that transports sodium from the gut
into the body.
Researchers have identified a fused gene in moss that provides insight
into how
cells build their external
walls.
A specific lung - targeting molecule is attached to the carrier's surface and the steriod, dexamethasone, an anti-inflammatory, is loaded
into the nanogel, which then binds to lung endothelial
cells lining the inside
wall of the blood vessels where it rapidly delivers the drug.
Learning how to control the composition of secondary
cell walls is an area of intense interest among advanced biofuel researchers because the structures make up the bulk of the plant matter that is broken down
into biofuels.
They wanted to know exactly how these subunits work together to insert the outer membrane proteins
into the outer membrane or
cell wall.
«It turns out that calnexin is somehow involved in controlling the function of the blood - brain barrier,» said Marek Michalak, a distinguished professor of biochemistry at the U of A. «This structure usually acts like a
wall and restricts the passage of
cells and substances from the blood
into the brain.
When inserted
into the body, stem
cells latch onto the structure and differentiate
into cells that start to build bone, much as construction workers assemble
walls, floors, and glass around a skyscraper's steel girders.
Now, Thomas Hales of the University of Michigan, Ann Arbor, has shown that a hexagonal honeycomb has
walls with the shortest total length, per unit area, of any design that divides a plane
into equal - sized
cells.
Incorporating a synthetic phage genome
into Gram - positive bacteria has so far been very problematic, as their
cell walls are so thick.
Yet even when appropriately modified peptide compounds make it through the stomach intact, another hurdle awaits them: The
cells of the intestinal
walls prevent their absorption
into the blood.
Platelet activating factor receptor and innate immunity: uptake of Gram positive bacterial
cell wall into host
cells and
cell - specific pathophysiology.
From the perspective of a bioengineer interested in converting glucose input
into lipid output, the development of a thicker
cell wall under starvation conditions represents wasted carbon that would otherwise be used for lipid production.
While neurotransmitters are created in the interior of the
cell, they are pumped, in large quantity,
into synaptic vesicles tucked
into the
wall of a nerve
cell's so - called «terminal,» the launch pad from which chemical messages are released from the
cell.
2006 — Ken Keegstra — for his pioneering contributions to our understanding of chloroplast biogenesis, protein import
into chloroplasts, and the structure and biosynthesis of the plant
cell wall
Soon enough, one of those
cells gets a PIK3CA mutation, and now the
cell is able to burrow
into the colon
walls, or find its way to a lymph node, or depart the mother ship for the liver.
The pre-clinical study results show that the synthesized steroid, squalamine, prevents and eliminates alpha - synuclein build - up inside neurons by unsticking the protein from the inner
wall of nerve
cells, where it clings and clusters
into toxic clumps, researchers say.
CAMBRIDGE, Mass. — New research
into a family of
cell wall proteins shows how yeast can present a variety of «faces» to its environment.
The pre-clinical study results show that squalamine prevents and eliminates α - synuclein build up inside neurons by unsticking the protein from the inner
wall of nerve
cells, where it clings and builds up
into toxic clumps, researchers say.
To repair heart muscle in a mouse, researchers inject adult stem
cells into the muscle of the damaged
wall of a mouse heart.