Sentences with phrase «into cells involves»

Not exact matches

Basically, CAR - T therapy involves taking a patient's own immune «killer» T - cells, inserting new genetic code into those cells which turn them into cancer - hunters that can home in on malignant B - cells (another kind of immune cell), and then pumping these specialized leukemia - busting cells back into the patient.

In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatment.

Those two companies, along with their larger competitor Novartis (nvs), are developing experimental chimeric antigen receptor T - cell (CAR - T) technology platforms, which are highly personalized treatments that involve extracting patients» immune cells, re-engineering them to target their specific cancers, and then pumping these sniper - cells back into the body.

The novel treatment space involves transforming a patient's own immune T - cells into cancer - busting weapons.

Bellicum is among the flurry of biotechs investing heavily into cell therapies such as experimental chimeric antigen receptor T - cell (CAR - T) treatments for cancer (this is the next - gen treatment that involves reprogramming immune cells to become cancer killers and has shown promise in blood cancers, which Bellicum specializes in).

Yeast extract gives us lots of health benefits to our healthy lifestyle such as: rich source of B vitamins, B vitamins are all involved in the metabolism of carbohydrates, fats and proteins into usable energy, but some are also important for digestion, immunity and red blood cell production within bone marrow.

At least 140 «Foote soldiers» might follow «King of Pot» Dunston Foote to the cell block Spring Valley Police announced Monday, December 12 that they spearheaded an investigation into Rockland's drug underground that's led to 140 arrests of people involved in the operation of deposed King of Pot, Dunston Foote (streetname «Killa»), former resident of -LSB-...]

She demonstrated that early experience leads to lasting changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer cells into healthy brain tissue.

Many of the mutations in ASD, Yan explained, result from chromatin remodeling factors, which are involved in dynamically changing the structure of chromatin, the complex of genetic material in the cell nucleus that condenses into chromosomes.

The method involves transforming the most common type of cells found in wounds into fat cells — something that was previously thought to be impossible in humans.

Autophagy involves breaking down the cell's parts — its protein - making, power - generating, and transport systems — into small molecules.

«What our findings show is that the problems with iPS cells don't just involve one or two or a few abnormal iPS cells escaping into the body and forming tumors, but that the whole population of cells is screwed up,» Lanza says.

The first step in the process involves inserting into those brain cells a gene that makes a light - sensitive protein.

The researchers reported the natural inflammatory response when a foreign substance like a hydrogel is introduced into a system and draws cells that secrete proteins involved in cellular infiltration, scaffold degradation, vascularization and innervation.

Almost all of these involve removing cells from an individual's body, editing their DNA and then putting them back into the body.

► The U.S. National Institutes of Health (NIH) has put funding on hold for experiments that involve «mixing human stem cells into very early animal embryos and letting them develop» while it «reconsiders its rules» for this type of research, Gretchen Vogel reported Wednesday.

The scientists found that if they replaced MYC with LIN41 in the cocktail of genes involved in reprogramming — meaning if they used O, S, K and LIN41 — they could convert adult cells into iPSCs with the same efficiency.

This is normally used to detect fetal abnormalities such as Down's syndrome, and involves inserting a needle into a pregnant woman's belly to take a sample of amniotic fluid containing cells from her fetus.

But the viral method involves inserting the DNA for the protein into cells instead, which means the cutting protein keeps being made for weeks after treatment.

Hydrogen is another attractive by - product of wastewater, and some of Logan's research at Penn State involves looking into how to capture hydrogen to run fuel cells.

With more than 800 members in the human genome, GPCRs are the largest family of proteins involved in decoding signals as they come into the cell and then adapt the cell's function in response.

As an example, the current study identified and provided insight into the function of several genes, not previously known to be involved in the taste system, related to cell motility.

From this collaboration the teams developed the LOCO - EFA technique which involves decomposing two - dimensional cell shapes — the shapes you can see under a microscope — into a series of ellipses.

ICSI involves selecting a single viable sperm cell that is then injected into the egg through a needle.

The new device will allow for more accurate medical procedures that involve the use of ultrasound to kill tumours, loosen blood clots and deliver drugs into targeted cells.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

In his search for solar cells, dubbed the Clean Energy Project, Aspuru - Guzik is screening molecules for a host of properties involved in converting sunlight into electrical energy.

One of the genes involved in feeding the big brain, called SLC2A1, builds a protein for transporting glucose from blood vessels into cells.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

Doing the screen involves using short pieces of RNA, called small hairpin RNAs, which are inserted into the cell and are able to halt messages from specific genes, keeping the genes from making proteins.

This method, known as targeted radionuclide therapy, or TRT, involves the use of molecules labeled with radioactive atoms that are injected into patients and localized in cancer cells.

Electron microscopy of the inner and outer surfaces of bacterial cells gives some clues, and crystallography — a process that involves stacking purified proteins into crystals so that their three - dimensional characteristics can be measured — provides others.

In both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cells.

They injected live brain cells from mouse embryos into the amygdalae of adult mice — the parts of the brain involved in fear.

Most of these trials involve stem cell - derived neural progenitor cells, which can turn into several different types of brain or spinal cord cells, or oligodendrocyte progenitor cells, which create the myelin sheaths that insulate and protect nerve cells.

In a study published December 22 in Stem Cell Reports, researchers developed an alternative approach involving the direct conversion of adult skin cells into functional testosterone - producing cells.

Think of the army of cellular agents, including white blood cells and platelets, that jump into action over a mere paper cut — rebuilding the tissue, warding off infection, and alerting the rest of the body to the wound through the A-delta fibers of the nervous system, which are involved in the transmission of acute pain sensations.

One potential treatment involves injecting the wound with stem cells, which can change into other cell types, such as skin cells like keratinocytes, to help with the healing process.

Now, a research team from Uppsala University has identified over a thousand genes that are involved in rebuilding a fully - fledged Stentor cell after being cut into two halves.

Such ion channels are often involved in transmitting signals into cells.

While assisted reproductive techniques such as intracytoplasmic sperm injection (ICSI)-- which involves the direct injection of sperm into the egg cell — can overcome head or tail abnormalities in sperm, recent animal research suggests that fertility doctors must use these techniques with care.

Scientists use OCT4 protein to reprogram adult cells into embryonic - like cells, an indication that it is involved in early development (SN: 11/24/07, p. 323).

Cell reprogramming involves making one cell type into anotCell reprogramming involves making one cell type into anotcell type into another.

Three teams of scientists reported earlier this year that they had directly reprogrammed adult mouse skin cells into embryonic cells, although the process involved viruses and cancer - causing genes.

In an advance that could solve many of the ethical and technical issues involved in stem cell research, two groups of scientists have independently converted human skin cells directly into stem cells without creating or destroying embryos.

«They've done a really exceptional job turning DNA into readable, writable memory inside living cells,» says Ahmad Khalil, a biomedical engineer at Boston University who was not involved in the new work.

Putting an egg cell into stasis involves adding many epigenetic marks throughout its DNA.

The case that prompted Bot's opinion involves a German patent granted to neuroscientist Oliver Brüstle in 1999 for a method for turning mammalian ES cells into neurons.

They demonstrated that prohibitin found on the surface of motor neuron cells was involved in entry of EV71 into those cells.

Efforts in the past to create stem cells have typically involved finding ways to take target cells and «dedifferentiate» them into multipotent cells, but this is typically a painstaking process.