Sentences with phrase «into cells of interest»

Not exact matches

When looking for genes that might play important roles in the metabolism of healthy and cancerous liver cells, Wang and his colleagues became interested in a gene called SLC13A5, which produces a protein that transports citrate into cells.

But what [was] really interesting in this study of the sled dogs, of Larry the sled dog in particular, was the discovery that some of these high performance dogs appear to have the ability to draw fat directly out of their and blood right into their muscle cells and immediately burn it that way, which is a more efficient way than normally what you'd see.

He wanted to study the mechanism of viral entry into cells, and Ebola provided an interesting case.

This group of about 800 receptors plays a central role in transferring signals from the environment into the cell and is of great interest for drug development.

They were interested in one of the cell's key signaling pathways, the MAPK pathway, which helps control cell growth, embryonic development, and the maturation of oocytes into eggs.

Since Yamanaka's breakthrough, dozens of groups have reported other ways of reprogramming cells as well as techniques to control differentiation of stem cells into neurons, cardiovascular cells, and other tissues of interest for regenerative medicine.

Young - Pearse and colleagues believe that their strategy of using induced pluripotent stem cells to reprogram patient skin cells into neurons of interest could be used to predict which therapeutics will best help early onset Alzheimer's patients.

«In addition to the new insights into plant cell microtubule organization, these observations of GCP - WD function will be of interest to scientists studying microtubules in animals, where GCP - WD has been challenging to observe it in action,» Ehrhardt added.

What makes it interesting it that it is directly responsible for the fusion of the HIV virus into human cells.

These cells can develop into all the body's cell types and are therefore of considerable interest to the field of regenerative and reparative medicine.

This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the early stages of life, during embryonic development.

Learning how to control the composition of secondary cell walls is an area of intense interest among advanced biofuel researchers because the structures make up the bulk of the plant matter that is broken down into biofuels.

In addition to their pathogenic function, aerolysin, and the majority of pore forming toxins, are most interesting because of an unusual duality: they are secreted by the bacterium as fully water - soluble proteins, which then assemble and insert into the host cell membrane to become genuine transmembrane proteins.

I think a lot of people were led to believe — and to what extent scientists were responsible for this is an interesting question — that if only the regulations were relaxed, embryonic stem - cell science would be central to our medical research and practice going into the future, and that it would massively alleviate suffering and produce cures for dreaded diseases.

Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the gene encoding the LCMV envelope protein, normally responsible for virus entry into target cells, has been deleted and replaced with a target gene of interest.

Once the Cas9 - sgRNA ribonucleoprotein (RNP) complexes have been delivered, single cells must be isolated and expanded into clonal cell lines to isolate and screen for the genotype of interest.

This corrected clonal cell line can also be differentiated into the cell type of interest.

There is a lot of interesting research going on into understanding the disease process, particularly the role of non-neuronal cells like microglia.

From the perspective of a bioengineer interested in converting glucose input into lipid output, the development of a thicker cell wall under starvation conditions represents wasted carbon that would otherwise be used for lipid production.

After gesicle - based delivery of the editing machinery into hiPS cells, cells must survive the process of single - cell cloning — a major bottleneck to obtaining clones with the modification of interest.

However, the ways in which the different types of stem cells came to be accepted into the stem cell family is itself an interesting story, and one that can help paint a useful bigger picture, and that is why this story will be the focus for this blog post to celebrate International Stem Cell Awareness cell family is itself an interesting story, and one that can help paint a useful bigger picture, and that is why this story will be the focus for this blog post to celebrate International Stem Cell Awareness Cell Awareness Day.

We can then take proteins of interest, change them in some specific way, and then put them back into a cell to create a sort of modified synapse.

Here Steve tells us how his interest in stem cells led him into cancer research and how he believes this angle of brain tumour research has unique potential for tackling cancers which are currently difficult to treat.

However, the ways in which the different types of stem cells came to be accepted into the stem cell family is itself an interesting story, and one that can help paint a useful bigger picture.

However, most previous attempts to transplant blood stem cells into a human fetus have been unsuccessful, prompting some researchers to lose interest in this promising field, according to MacKenzie, who also is an investigator with the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.

Of particular interest is that putative embryos from Doushantuo Formation can be digitally dissected into their component cells, and even the sub-cellular organelles examined.

We have recently developed the use of site - specific nucleases to genetically engineer human pluripotent stem cells, which can be maintained indefinitely and differentiated into any cell type of interest.

The Stem Cells Portal provides an online forum in which active researchers in the Stem Cells field, or persons who have an interest in this area of science, can access review articles of recent and current publications, enter into online discussions about the merits of the published data, and discover a range of other resources useful to the Stem Cell research community.

We are currently involved in a collaborative research programme with Cellectis biotech company aiming at genetically modifying hiPS cells in order to optimize differentiation protocols into particular cell lineages and allow the isolation of homogenous cell populations of interest.

We became especially interested in one microRNA — miR - 24 — that stood out because it is upregulated as multipotent blood cells differentiate into a wide variety of mature blood cells.

Differentiation into extraembryonic endoderm [21] or neural progenitors [33] are frequent early outcomes of spontaneous differentiation when human ES cells are cultured in the presence of a feeder cell layer, and it is interesting to speculate that the cells are being primed for these fates.

Interest is now moving increasingly into potential use of T cells modified using recombinant viral vectors for immunotherapy applications.

One interesting fact here is that many compounds are co-transported, for example sodium can not be efficiently absorbed without some sugars (remember this), as sodium uptake is coupled with glucose uptake, and absorption of both accelerates water uptake (as it forces water into the cells to buffer the two.)

As Masterjohn warns: «Bodybuilders and other athletes interested in gaining muscle have an interest in boosting their levels of testosterone and other growth factors and maximizing their utilization of protein and its incorporation into muscle cells.

For a cell to use ATP, it must first break it down into several smaller molecules, and this process produces byproducts that are then «recycled» back into ATP to be used again, including one of particular interest here: adenosine diphosphate (ADP).

With bitters, digestive enzyme secretions are increased, helping to promote the complete breakdown of nutrients into their absorbable units, preventing gas formation when large molecules are acted upon by bacteria further down the small intestine.2, 11 The complete breakdown of proteins is particularly important, as the cross reactivity of immune cells between undigested protein molecules and intestinal cells plays an important role in the etiology of conditions such as celiac disease.15 Insulin and glucagon secretions are stimulated, helping to stabilize blood sugar levels.3, 11 Many bitters formulations have been traditionally used in the treatment of type 2 diabetes, and it is interesting to point out that many naturally sweet substances are often paired with some bitterness in nature.4, 11 Herbalist Jim McDonald hypothesizes that our cravings for sweetness may mask cravings for bitterness for this reason.4

Input the annual interest rate of a savings account that these funds could have been saved at into cell B14.

First: the cells demonstrate regenerative capacity by differentiating into the cell line of interest such as bone, cartilage or muscle cells.

It is interesting that in the #OccupyVancouver movement, the Supreme Court of British Columbia is not allowing cell phones into the court room hearing the injunction application by the City of Vancouver.

What will be most interesting to watch as this cases progresses is whether the Courts will take into account more recent Supreme Court cases dealing with laptop and cell phone searches and if there is a positive duty on the part of a traveler to unlock or provide the password to a digital device.

There are a variety of lenses that you can clip into your cell phone to get these interesting angles.