These cells included chondrocytes (cartilage cells) that were made from mesenchymal stem cells that had been taken from her bone marrow; turning these MSCs
into chondrocytes only took researchers three days.
Not exact matches
This may entail making small holes in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it
into the defect (osteochondral autograft transfer), taking cartilage cells from the knee and then having them grown in a lab for later re-implantation (autologous
chondrocyte implantation), or taking cartilage from a person who has passed away and placing it in the defect (osteochondral allograft transfer).
Perivascular cells, including pericytes in the smallest blood vessels (e.g., microvessels) and ARCs around larger ones, express mesenchymal stem cell markers and bear a multi-differentiation fate potential (differentiate
into osteoblasts,
chondrocytes, adipocytes, smooth muscle cells and myocytes) similar to that documented for MSCs in vitro.
Specifically, MSCs are usually confirmed to be MSCs by showing that they can differentiate
into three different, standard mesenchymal cell types: osteocytes (bone),
chondrocytes (cartilage), and adipocytes (fat).
In addition to iPS cells derived from progeria - patients, the researchers successfully applied their method to adult mesenchymal stem cells, which can differentiate
into a variety of cell types, including adipocytes, osteoblasts,
chondrocytes, cardiomyocytes, and, as described lately, beta - pancreatic islets cells.
Based on previous protocols [5, 6] they have now created a 3D protocol for chondrogenic lineage differentiation via the generation of a putative chondrogenic progenitor cell population, and have found that using this protocol C - iPSCs can be readily differentiated
into cartilage in a manner comparable to that of mature
chondrocytes [7].