Sentences with phrase «into clinical»
As CRISPR - Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene - editing technology can introduce hundreds of unintended mutations into the... Read more
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«This is the first objective, physiological marker for two major psychiatric disorders that, once fully developed into a clinical test, can allow for earlier and more accurate diagnosis, and selection of more appropriate medications for patients.»
We have translated these pre-clinical observations into clinical studies.
It took us 16 years to get this technology into clinical trials, but we can make our diagnosis in less than one day compared with existing methods that take more than one week.
This lack of trust threatens the successful integration of genomics into clinical care, as recently called for by the Chief Medical Officer.
Furthermore, there are efforts to take this field into the clinical sphere.
Immune Design entered into clinical collaboration agreements with Merck, known as MSD outside the U.S. and Canada, to evaluate the safety and efficacy of two Immune Design immuno - oncology investigative agents, G100 and LV305, separately combined with KEYTRUDA ® (pembrolizumab), Merck's anti-PD-1 therapy, in Phase 1 trials in patients with non-Hodgkin's lymphoma (NHL) and melanoma, respectively.
ASHG 2015: Researchers Study Costs of Integrating Genetic Sequencing into Clinical Care ASHG Press Release — October 9, 2015
Such work is key to translating basic research advances into clinical impacts.
«DG041 is the second compound we have entered into clinical trials, and the most advanced to have been developed entirely from our own target and drug discovery capabilities.
Members support SPFM's mission to improve patient care and outcomes by facilitating implementation of functional assays into clinical care.
Immune Design entered into a clinical trial collaboration with Genentech, a member of the Roche Group, to evaluate the safety and efficacy of its CMB305 cancer immunotherapy product candidate combined with the investigational cancer immunotherapy atezolizumab in a randomized Phase 2 trial in patients with soft tissue sarcoma.
Abstract: Short - term costs of integrating genome sequencing into clinical care: Preliminary results from the MedSeq Project.
Scholar Rock is actively working to advance SRK - 015 into clinical trials to improve muscle strength and motor function in patients with Spinal Muscular Atrophy (SMA).
«This is the third compound we have entered into clinical trials based upon our discoveries in the genetics of common diseases.
«We hope this could be developed into a clinical trial testing a combination of PD - L1 and PD - 1 blockade with epigenetic therapy.
Methicillin - resistant Staphylococcus aureus (MRSA) was first observed in 1960, less than one year after the introduction of this second generation beta - lactam antibiotic into clinical practice.
Genomic sequencing of healthy individuals could grow to resemble current population - based preventative screening measures, such as newborn screening or the use of colonoscopy after age 50, which have been integrated into clinical practice to identify uncommon diseases.
The MedSeq Project seeks to develop a process to integrate genome sequencing into clinical medicine and explore the impact of doing so.
Micro-RNAs in colorectal cancer: translation of molecular biology into clinical application.
Physician - scientists at the Cancer Institute engage in translational research, transforming their laboratory discoveries into clinical practice, quite literally bringing research to life.
The World Bank, the World Health Organization, and HIV groups everywhere rooted for VaxGen Inc of Brisbane, California, and it's «first Aids vaccine», which went into clinical trials in both the United States and Asia during the 1990s.
How new technologies could be introduced into clinical practice and how data storage and safety can be dealt with was some of the topics of the Clinical Genetics Day, organised by SciLifeLab.
We hope that this project will provide valuable and unparalleled data to be used to integrate genomic information from newborns into clinical pediatric care.
However, these companies have to prioritise which agents they take into clinical development - this leaves potentially effective treatments on pharmaceutical companies» shelves.
«This study allowed us to evaluate the protective efficacy of several prime - boost vaccine combinations, and these data will help guide the advancement of the most promising candidates into clinical trials,» noted lead author Dr. Dan Barouch of Beth Israel Deaconess Medical Center at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard.
Cancer Research UK and Cancer Research Technology - the charity's development and commercialisation arm - have reached an agreement with AstraZeneca to take compound AZD - 3965 — a first - of - its - kind experimental drug to potentially treat a range of cancers - into clinical trial.
And because several HDAC - blocking drugs are commonly used in other fields of medicine, including neurology, it proved relatively straightforward for physicians to take some of these drugs into clinical trials in patients with SMA.
The identification of correlation patterns in these spontaneous fluctuations has been termed resting state functional connectivity (fcMRI) and has the potential to greatly increase the translation of fMRI into clinical care.
Dr. Gastier - Foster also has significant translational research funding to support the integration of genetic / genomic testing into clinical trials and promote biobanking and tumor processing for new research discoveries.
Both of her clinical labs focus on the rapid translation of new genetic discoveries into clinical tests and bringing novel technologies and software systems into molecular diagnostics to support the integration of genetics into clinical use.
This subtyping system will be exploited to better define prognosis and integrated into clinical tools and strategies to benefit patient outcomes.
As for any innovation with potential medical applications, hiPSCs must satisfy a great number of criteria prior to their introduction into clinical practice.
The Joslin team is now setting up collaborations with surgeons to move the approach into clinical studies.
We identify and advance therapeutics into clinical trials for children with brain cancer, with increasing focus on types of brain tumors that are uncommon and have the greatest need for translational research.
The first treatment for HIV was shown to have activity against retroviruses in animals, and once it was shown to also be active against HIV went directly into clinical trials.
We include guidelines for performing resting state research on clinical populations, outline the different areas for clinical application, and identify important barriers to be addressed to facilitate the translation of resting state fcMRI into the clinical realm.
These new preclinical studies provide support for advancing the Ad26 / MVA prime - boost vaccine candidate into clinical development.
«By integrating basic research with work on patients, she helped to transfer her findings into the clinical routine,» Annette Peters comments on Karen Nelson's achievements.
It aims to increase the number of successful new treatments for cancer by taking undeveloped anti-cancer agents from industry and putting them into clinical trials.
The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.
He is also interested in patient - centric care, specifically exploring how to incorporate technology into clinical care without losing the humanity of the physician - patient relationship.
The mandate to translate discoveries in the basic sciences into the clinical arena is widely acknowledged.
He is Director of the Joint Center for Translational Medicine, a collaborative effort joining Caltech and UCLA in a program translating basic science discoveries into clinical realities.
ASME Journal of Engineering and Science in Medical Diagnostics and Therapy seeks to bridge the gap between engineers and non-engineers and translate engineering knowledge into clinical applications, to accelerate biomedical innovation, trial and commercialization.
Gladstone established the Assay Development and Drug Discovery Core to help scientists accelerate their research into target and drug - discovery phases and move their findings into clinical trials and potential therapies for disease.
Rappuoli anticipates that Chiron's new vaccine will be put into clinical trials within the next year.
«We are thrilled to now have a means to translate all that research into clinical prevention.»
Support for speakers at international meetings: ASHG supports the exchange of genetics education expertise across borders by offsetting some of the travel costs for prominent geneticists / genetics educators who are invited to serve as faculty or speakers at international workshops or meetings (including efforts that focus on developing countries and integrating genetics / genomics into clinical care).
ASHG members also investigate the genetic underpinnings of health and disease and how to translate new genetic discoveries into clinical advances.