IRDiRC Recognized Resources is a quality indicator, based on a specific set of criteria, that was created to highlight key resources which, if used more broadly, would accelerate the pace of translating
discoveries into clinical applications.
Another area that is becoming increasingly important is the translation of basic science research
findings into clinical applications, and there is a growing need for physician scientists, says Alan Trounson, president of the California Institute for Regenerative Medicine (CIRM).
Already, a few examples exist — blood tests for hereditary colon cancer; the design of Herceptin, a breast cancer drug; and Gleevec, a drug used in chronic myelogenous leukemia — in which the identification of gene alterations
translated into clinical applications.
ASME Journal of Engineering and Science in Medical Diagnostics and Therapy seeks to bridge the gap between engineers and non-engineers and translate engineering
knowledge into clinical applications, to accelerate biomedical innovation, trial and commercialization.
While translational research has traditionally moved basic immunology knowledge
forward into clinical application, varying clinical presentations of human immune - related disease processes, as well as variability in therapeutic outcomes, have provided opportunities for discovery of novel mechanistic hypotheses directly from patients.
While the findings have only been seen in animals models so far, Zeng said that successful translation of the
regimen into clinical application in humans may represent a novel approach that allows strong anti-cancer effects without causing GVHD.
This label is a quality indicator, based on a specific set of criteria to highlight key resources, which, if used broadly, will accelerate the pace of translating discoveries in rare
diseases into clinical applications.
Thus the green light from the scientists and ethicists won't translate anytime
soon into clinical applications that could potentially help families that want healthy babies, said Shoukhrat Mitalipov, a pioneer of the new technique at Oregon Health & Science University in Portland, Ore..
As part of Sanford Health, the largest rural non-profit health care system in the nation, we can integrate research and patient care so that information flows seamlessly — translational genomic research discoveries are
accelerated into clinical applications, such as new treatments and diagnostics to benefit patients, and clinical data about patient response flows back to the labs to inform more discoveries.
The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries
into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.
The CRS4's Bioinformatics laboratory has access to large clinical sample sets and genomic data and closely collaborates with hospitals to support clinical researchers in translating basic research
findings into clinical applications.
«While much work remains to be done to develop this
research into clinical applications, our findings could have a promising translational impact, both for protein replacement and gene therapy,» said Arruda.
Bringing together bench and bedside is the purpose of a new institute that aims to become a world - class «translational» cancer research centre, where the knowledge gained from basic research is
translated into clinical applications.
In future work, the Eischen laboratory aims to further understand the role of lncRNAs in ovarian cancer, and potentially translate their findings
into clinical applications to reduce ovarian cancer metastasis.
Yet, the fundamental insights into the mechanisms of metastasis will pave the way for the rationale translation of these preclinical discoveries
into clinical application.»
The new institute is working in close collaboration with departments and institutes across the Hershey campus, including the Penn State Clinical and Translational Science Institute, and on Penn State's University Park campus to advance research in the field and to translate that research
into clinical applications.
They focus on how CIRM's infrastructure might be applied to the Clinic, the tools needed to move the Clinic concept worldwide, and translational technologies currently in the field and what is needed to move
them into clinical application.
Launched in February 2012 under the leadership of James Broach, Ph.D., the institute works in close collaboration with departments and other institutes across the Hershey campus, including Penn State Clinical and Translational Science Institute, to advance personalized medicine research and to translate that research
into clinical applications.
By working in close cooperation with the German Rheumatism Research Center Berlin (DRFZ) and other academic and non-academic partners, the department lays the foundations for a rapid translation of research findings
into clinical application, where they can be used in the diagnosis and treatment of these challenging autoimmune diseases.
The presentation took the research information from Level 1
into a clinical application that I can really use in my practice.»