It is often claimed that this enhances absorption but the truth is that by the time you take liquid creatine, it has more than likely completely degraded
into creatinine.
The claim that regular creatine monohydrate needs to be buffered in order to prevent it from breaking down
into creatinine with the body is inaccurate.
The study goes on to state that «a substantial conversion of creatine
into creatinine has been reported in many formulations and may explain the present findings.»
Honestly, I'm not sure how quickly it converts
into creatinine, but I wouldn't use boiling water, or heat water with creatine in it.
Creatine is converted
into creatinine, and a high creatinine level is a marker for kidney damage.
Buffered creatine is sometimes promoted as more effective and as resulting in less of the creatine breaking down
into creatinine, a less useful byproduct.
The problem is that you're only absorbing 20 - 30 % of the creatine you take in before it is eventually converted
into Creatinine.
Not exact matches
Excess creatine that hasn't been utilized by the muscles is turned
into a waste product called
creatinine, for which the kidneys have to work overtime in order to remove it.
So if I have somebody who's
into fitness, maybe an athlete and we get back, it's not a technical term, but sort of wonky enzymes, wonky
creatinine, or some of these things, I'll ask them, you know, when was the last, when did you exercise prior to this test, and if they say that they had a tough session the day before, then you have to take that
into consideration.
The problem is that traditional Creatine Monohydrate is extremely short - term, caused by the rapid conversion
into the toxic bi-product called
Creatinine, which when it is exposed to any liquid, will result in poor absorption
into your bloodstream.
The reason for this is when you ingest creatine ethyl ester, it's quickly converted
into an inactive substance
creatinine, which confers none of creatine's benefits.
This is because suspending creatine in liquid for several days causes it to break down
into the inactive substance
creatinine.
Assuming the average person clears about 1 mg
creatinine into their urine per minute (480 mg / min) and 113.12 g / mol
creatinine (thus 480 mg / 1000 mg / g and divided by the molar mass, multipled by 1000 to convert mol to mmol, yielding an average excretion of 4.24 mmol
creatinine in 8 hours), I calculate that just under 50 mmol TMAO / mol
creatinine, as shown in Fig 2b of the Nature Medicine paper converts to 212 umol / 8 h (50 mmol TMAO / mol
creatinine * 1 mol
creatinine / 1000 mmol
creatinine * 4.24 mmol
creatinine / 8 hours * 1000 umol / TMAO / mol TMAO).
The reason for this is CEE is less stable than creatine monohydrate, resulting in its rapid conversion
into a substance called
creatinine, which has no beneficial effects in the body.
It is funny that this is the common marketing claim because the truth is that creatine ethyl ester rapidly degrades
into the metabolite
creatinine in the intestines, almost completely in fact (14,15).
After 2016, the SDMA test came
into greater use due to the Idexx marketing campaign and a hope that SDMA levels might detect kidney problems at an earlier stage than BUN and
creatinine do.
Since normal kidneys allow very little albumin protein in your pet's blood to escape
into its urine, there are tests that check for its increased presence without comparing it to the amount of
creatinine that is present.
For deeper insights
into kidney health, run SDMA whenever you run BUN and
creatinine.