Sentences with phrase «into daughter cells»

Needleman is especially interested in the spindle, a cellular structure that separates chromosomes and pulls the duplicated DNA from the mother cell into the daughter cell during division.

When they disrupted TBK1 activity, the cells could not separate chromosomes correctly into daughter cells and mitosis could not progress.

But when the researchers used live microscopy to watch how the 4 - millimeter - wide organoids developed, they noticed that human progenitor cells took 50 % longer than those of the other great apes to arrange their chromosomes before splitting into daughter cells.

Accommodating these extra structures into the daughter cell's nucleus might be what increases the overall cell size.

These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

«This suggests that cell division is used not only to transmit the genetic information into daughter cells and create two equivalent cells,» he said, «but it is also an opportunity for cells to reorganize their genomes in 3D space, sequestering parts of the genome at the nuclear periphery and rendering it inaccessible to transcription.»

The efficient compaction of DNA during cellular division ensures equal distribution of DNA into daughter cells and prevents aneuploidy, which has been implicated as a major driver of tumor development.

Furthermore, cells in which MELK had been depleted displayed asymmetric division (Figure 6G), characterized by an unequal allocation of cell mass into daughter cells.

Spindles are cellular structures that play an important role in cell division, separating chromosomes and pulling the duplicated DNA from the mother cell into the daughter cell.