Sentences with phrase «into drug design»

«It is challenging to take basic science discoveries from the laboratory and into drug design.

Adams underscores that the ability to understand the configuration of atoms in molecular space can be used to generate new insights into drug design and development.

Not exact matches

Rõivas, the former Prime Minister, says Estonia is working on developing «precision medicine» that would tap into the genome data of its 1.3 million citizens in order to better diagnose illnesses, treat people, and design personalized drugs.

Mr Straw today committed the government to a new strategy designed to get prisoners off drugs, as well as helping offenders into work.

One of those licenses went to Michael Hackett, a UNC doctoral student who got an idea 2 years ago for a potential commercial drug: to trick tumors into absorbing chemotherapy drugs by designing a molecular Trojan horse.

Once researchers understand the rules for how to get specific shapes with TZPs that also assemble into larger structures, they can design materials with desired functions — for example, a membrane for a battery, a catalyst for a fuel cell, or even a therapeutic drug.

But there's a dark side to cancer - killing drugs designed to match distinct cancer mutations like a key into a lock.

Most drugs are designed to interfere with a specific disease pathway by elbowing their way into important spots inside the cell.

Most of the newly designed drugs fall into the stimulant category, but others more closely resemble opioids.»

Led by two groups — the Coalition for Mercury - free Drugs and SafeMinds — they have brought the thiomersal «debate» into negotiations designed to address environmental problems.

A specially designed chiral catalyst is used to oxidize hydrocarbons into multifunctional compounds that are obtained in high purity and are readily converted into an assortment of molecules that will streamline the synthesis of future pharmaceutical drugs,» said Dr. Leila Bayeh, a former graduate student and lead author of the study.

One project involves probing Foundation Medicine's growing database of tumor profiles for specific mutations and using that information to either design drugs or to parse patients into clinical trials of the company's drugs, says Pao.

In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a drug designed to thwart it.

The capsules are designed so that after all of the drug is released, the capsules disintegrate into smaller components that can pass through the digestive tract.

It attaches these drugs to polymer nanoparticles that migrate specifically into cancer cells and are designed to release the drugs at a particular level of acidity that is common to those cells.

The findings make evacetrapib the third failure in a class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors, which are designed to disrupt the natural process by which HDL cholesterol is converted into LDL cholesterol in the body.

Medicinal chemists might be able to use this insight into how fidaxomicin works to design versions of the antibiotic that are absorbed through the gut, or to identify other drugs that also bind in the RNAP pocket and interact with RpbA.

Dr. Lang and his colleagues designed a drug called ISP to block the enzyme and facilitate the drug's entry into the brain and spinal cord.

The ProVision 100 is a computer system with software which converts data such as simulations of drug molecules or architects» designs from a two - dimensional format into three dimensions.

The findings open up new avenues of research into exactly how the brain controls eating, and suggest that drugs designed to activate or inhibit neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as diabetes and hypertension.

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period.

Scott's team designed a nanocarrier formulation that — after quickly forming into a gel inside the body at the site of injection — can continuously release nanoscale drug - loaded vehicles for months.

Discovering the structure of this enzyme will provide valuable insight into how this protein functions and could provide blueprints for designing drugs that inhibit or increase certain protein functions, which would make those drugs more effective.»

The posters were designed to raise awareness about social anxiety disorder, a condition characterized by overwhelming anxiety and excessive self - consciousness in everyday social situations, which the drug Paxil, then made by SmithKline Beecham (which would later merge into GlaxoSmithKline), had just been approved to treat.

«If we can design drugs that specifically stabilize PRDM16 protein, this can convert white blood cells into brown fat with fewer side - effects.

Secures $ 28 Million Series B Financing to Commercialize its Organs - on - Chips Technology into a Lab - Ready System; Enabling Human - Relevant R&D to Improve Drug Development and Consumer Product Design

A series of six cell culture assays was designed to mimic multiple old - age - associated pathways of central nervous system (CNS) nerve cell damage, and drug candidates were required to show efficacy in all of these assays before being moved forward into animals.

The molecular models arising from their work can be used to design new drugs that interact with critical regions on the tau molecule to prevent its assembly into tangles.

By understanding the details of this motion, one can determine the amount of energy needed to transform reactants into products in a chemical reaction, or the color of light absorbed by a molecule, and ultimately accelerate the design of new drugs and materials, better catalysts and more efficient energy sources.

With the goal of creating a vault capable of encapsulating therapeutic compounds for drug delivery, UCLA doctoral student Daniel Buhler designed a strategy to package another nanoparticle, known as a nanodisk (ND), into the vault's inner cavity, or lumen.

Further the Meiler laboratory develops a structure - based drug design module for ROSETTA and docking protocols particularly suited for docking small molecules into comparative models.

La Maison Rililie Designs About - I am a maniac knitter that dived abruptly into this kind of «drug» at a very bad period in my life... hence the title of my blog: «knittingtherapy» - because knitting can really be therapeutical.

«Stepping Into Darkness: The Visual Design of Sicario» focuses on crafting the film's look and defining cinematography, «Blunt, Brolin and Benicio: Portraying the Characters of Sicario» features interviews with the three leads, «Battle Zone: The Origins of Sicario» researches the brutal history of drug violence along the border (it features graphic imagery so beware), and «A Pulse from the Desert: The Score of Sicario,» which runs about 6 minutes, profiles composer Jóhann Jóhannsson.

She is brought back to life by Prof. Jack Crowley (Bruce Abbott) through the use of an experimental drug, as part of a program designed to turn her into an unstoppable warrior.

For example, the difference between investigating the chemical properties of a new compound versus designing a marketable drug, or in education, between funding research in neuroscience versus developing that research into instructional resources).

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Writing for the majority, Justice Thomas Saylor noted that a company that placed a drug into the marketplace that it knew or should have known was dangerous enough could be in violation of its duty of care either through «design or marketing.»

Legalize and Regulate Marijuana WHEREAS, despite almost a century of prohibition, millions of Canadians today regularly consume marijuana and other cannabis products; WHEREAS the failed prohibition of marijuana has exhausted countless billions of dollars spent on ineffective or incomplete enforcement and has resulted in unnecessarily dangerous and expensive congestion in our judicial system; WHEREAS various marijuana decriminalization or legalization policy prescriptions have been recommended by the 1969 - 72 Commission of Enquiry into the Non-Medical Use of Drugs, the 2002 Canadian Senate Special Committee on Illegal Drugs, and the 2002 House of Commons Special Committee on the Non-Medical Use of Drugs; WHEREAS the legal status quo for the criminal regulation of marijuana continues to endanger Canadians by generating significant resources for gang - related violent criminal activity and weapons smuggling — a reality which could be very easily confronted by the regulation and legitimization of Canada's marijuana industry; BE IT RESOLVED that a new Liberal government will legalize marijuana and ensure the regulation and taxation of its production, distribution, and use, while enacting strict penalties for illegal trafficking, illegal importation and exportation, and impaired driving; BE IT FURTHER RESOLVED that a new Liberal government will invest significant resources in prevention and education programs designed to promote awareness of the health risks and consequences of marijuana use and dependency, especially amongst youth; BE IT FURTHER RESOLVED that a new Liberal government will extend amnesty to all Canadians previously convicted of simple and minimal marijuana possession, and ensure the elimination of all criminal records related thereto; BE IT FURTHER RESOLVED that a new Liberal government will work with the provinces and local governments of Canada on a coordinated regulatory approach to marijuana which maintains significant federal responsibility for marijuana control while respecting provincial health jurisdiction and particular regional concerns and practices.

web drug dealers and pseudonymous hackers have figured that Bitcoin is not magically private money, many have turned to Monero, a digital coin that promises a far higher degree of anonymity and untraceability baked into its design.

Serving as a Research Associate for Endometrin Pharmaceuticals, conducting research into new drugs designed to treat type 2 diabetes; creating trial protocols, working closely with ethics committees, verifying data, and writing detailed reports of findings.

La Maison Rililie Designs About - I am a maniac knitter that dived abruptly into this kind of «drug» at a very bad period in my life... hence the title of my blog: «knittingtherapy» - because knitting can really be therapeutic.