Sentences with phrase «into early phase»

The drug is ready to be taken into early phase clinical trials.

Together with the research and clinical resources of the nation's leading cancer hospital, we have the ability to take a program from a research hypothesis all the way to a clinical candidate supported by robust preclinical data, and into early phase clinical studies in well - defined patient populations.

That in turn has allowed a glimpse into the earliest phases of the Jesus movement, including its transition from a community gathered around the wisdom of Jesus to a sect that looked for his return as an apocalyptic messiah.

The reason I chose this as a topic was because I write this monthly feature that tracks how a technology starts its life from basic science, how it's transferred from basic science findings into the early phases of the technology, and this is a classic example because it goes from an understanding about how evolution works all the way to the early phases of developing a drug.

Not exact matches

Like renowned programs such as Y Combinator and Dreamit Ventures, these corporate - run initiatives help early - and midstage companies get from the concept phase through adolescence and into young adulthood.

Their businesses tend to grow fairly well in the startup and early growth phase, but as soon as their personal income hits preset targets, their internal thermostat kicks in and they go into customer service mode.

encouraging private investors and experienced Angel investors to put their money and talent into the early start - up phase for such companies, and

However, development costs will likely rise, however, as the «DepoVax pipeline expands into other medical markets beyond oncology and infectious disease» and «existing programs advance into more substantive Phase 2 studies, perhaps as early as FY H2 / 18.»

Even though the objectifications, as early phases, make up the actuality of the newly arising entity, they must at the same time be regarded as potentialities insofar as the form of their ultimate incorporation into the new entity is not yet fully determined, and will experience its determination only in the process of concrescence.

And many other physicists now concur that the early phases of the universe have always held out much more promise for evolving into life, mind, and spirituality than earlier science had allowed.

It presupposes a complex process of comparison of earlier and simpler phases of experience which can never enter into consciousness.

Although it will be incredibly difficult to ever match his contributions on the pitch, it's vitally important for a former club legend, like Henry, to publicly address his concerns regarding the direction of this club... regardless of those who still feel that Henry has some sort of agenda due to the backlash he received following earlier comments he made on air regarding Arsenal, he has an intimate understanding of the game, he knows the fans are being hosed and he feels some sense of obligation, both professionally and personally, to tell it like he sees it... much like I've continually expressed over the last couple months, this team isn't evolving under this current ownership / management team... instead we are currently experiencing a «stagnant» phase in our club's storied history... a fact that can't be hidden by simply changing the formation or bringing in one or two individuals... this team needs fundamental change in the way it conducts business both on and off the pitch or it will continue to slowly devolve into a second tier club... regardless of the euphoria surrounding our escape act on Friday evening, as it stands, this club is more likely to be fighting for a Europa League spot for the foreseeable future than a top 4 finish... we can't hope for the failures of others to secure our place in the top 4, we need to be the manufacturers of our own success by doing whatever is necessary to evolve as an organization... if Wenger, Gazidis and Kroenke can't take the necessary steps following the debacle they manufactured last season, their removal is imperative for our future success... unfortunately, I strongly believe that either they don't know how to proceed in the present economic climate or they are unwilling to do whatever it takes to turn this ship around... just look at the current state of our squad, none of our world class players are under contract beyond this season, we have a ridiculous wage bill considering the results, we can't sell our deadwood because we've mismanaged our personnel decisions and contractual obligations, we haven't properly cultivated our younger talent and we might have become one of the worst clubs ever when it comes to way we handle our transfer business, which under Dein was one of our greatest assets... it's time to get things right!!!

The Trump administration ultimately abandoned the defense of its first decree, and issued a new order earlier this month intended to avoid the problems that hamstrung the first: by honoring visas approved under the previous president, and by phasing into effect over two weeks.

Moreover, it is hoped that evidence of very rare events that may have occurred in the early phases of the creation of our universe will be discovered, providing insight into new laws of physics beyond those of the Standard Model.

ACT is now performing early - phase clinical trials testing the safety of implanting retinal cells derived from human ES cells into the eye to treat certain types of blindness.

Another model suggests that dispersal into the Arabian interior began much earlier (approx. 75,000 to 130,000 years ago) during multiple phases, when increased rainfall provided sufficient freshwater to support expanding populations.

Global temperatures could break through the 1.5 °C barrier negotiated at the Paris conference as early as 2026 if a slow - moving, natural climate driver known as the Interdecadal Pacific Oscillation (IPO) has, as suspected, moved into a positive phase.

NASA is currently in the early phases of a test mission with the European Space Agency to smash a spacecraft into a harmless 800 - metre asteroid in an attempt to deflect it.

«The current results do not exclude the possibility that the early dietary modification may affect the latter phase, and therefore it is extremely important to continue to follow the study participants into the final endpoint, which is the age of ten years.

«The next step is to figure out how to bring this finding into early - phase clinical trials with patients, and we're partnering with pharmaceutical companies to explore this,» Goga said.

Earlier phases of the study have shown it to be effective in treating individual cases of trachoma, and the trial is now looking into what treatment strategies will be required to stop the infection spreading and thereby eradicate the disease within the country.

NuScale incorporates the security - by - design philosophy by incorporating security requirements (detection, deterrence, and delay) into the early design phase.

The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.

Dr. Azad's research focused on early phase drug development and the intersection of moving exciting laboratory findings into patients for new treatment options

As of April 2009, the TMT will have moved from the design into its early construction phase.

Based on observations of a group of three young female Somali wild asses at the Saint Louis Zoo, the study provides new insight into the species» social behavior in a captive setting — a relatively good proxy environment for the early phases of wild animal domestication.

So, regulators and drug developers are looking at ways to import data collected in early studies — which are used to initially assess drug safety and efficacy — into the Phase 3 studies that the FDA uses to determine whether drugs should make it onto the market.

I am still in the building phase of my business and in the middle of transitioning into becoming a full time Eating Psychology Coach, so it might be too early to predict where this leads me.

A: Perimenopause (literally meaning «around menopause») is the transitional phase leading up to menopause which can start in your early 30's or begin as late as into your 50's.

The early days of the MCU were largely dominated by white men, but as we move into Phase 4 — and with Kevin Feige already planning another 20 - plus movies — fans can expect the roster of heroes to change.

Dark Forces came into being during the early phase of the franchise, and took players to a bunch of locations which would later form part of the wider canon.

The final phase two standards were called for by President Obama's Climate Action Plan, and respond to the President's directive in early 2014 to develop new standards that run into the next decade.

[49] Pre-Safe Impulse works an early phase of the crash, before the resulting deceleration starts to increase, the front occupants are pulled away from the direction of impact and deeper into their seats by their seat belts.

The Q5 hybrid, which has finally gone into series production after a four - year development phase, is vastly improved over the earlier prototype version we drove a while back, most notably in the synchronization of its gasoline engine and electric motor.

(Author's note: initially I thought I'd write some type of instructional post, but in the process of planning and writing, it turned into more of an effort to inspire those of you who are in the early phase of your writing life — probably because I'm in the early phase of my most ambitious project to - date and -LSB-...]

Referring to the need to withdraw more than the legal minimum from a Registered Retirement Income Fund (RRIF), Armstrong says people who retire early or phase gradually into retirement by reducing their work hours «will likely be at lower income levels than when they were engaged in full - time work.»

In the early phases of acclimating him to his crate, leave the crate door off or prop it open with a heavy object so it doesn't suddenly close or bump into your puppy.

As the Institute enters its fifth year, staff members are poised to emerge from the initial start - up phase — ready to build on early successes and launch into a broader range of programmed activities to affect change.

Although the game's current early access phase has made it somewhat devoid of people looking for an online match, I was able to get into a few games and get my ass handed to me.

These keys can be redeemed via Steam and will get you into every closed beta test event up until the start of the early access phase.

«We've poured our heart and soul into perfecting KILLING FLOOR 2, seeing all of the community feedback from the Early Access phase was invaluable, and to see the game's full release today is truly overwhelming,» said John Gibson, President of Tripwire Interactive.

Before then, the game will end its Early Access phase on September 8th and move into a Closed Beta period for those who have already dropped a line and have been baited into trying the game out.

Bulkhead Interactive has just launched Battalion 1944 into an early access phase.

Epic Games recently put its Fortnite project into an early access phase across PC, PS4 and Xbox One.

A number of paintings from this phase in California — exemplified by PH - 613, 1942 — establish Still's early move into an Abstract Expressionist style well in advance of other artists in New York City.

In Twisted Figures, his third solo show at 532 Gallery Thomas Jaeckel, Hughes's latest series of acrylic paintings pushes this language into a new phase in which the shapes on the canvases continue to self - confidently assert their own presence, yet begin to move beyond an earlier, more matter - of - fact reliance on organic and visceral associations.

The work moves through several recognisable phases: from the carefully constructed figurative pictures of the late 1940s; into various degrees of object - based abstraction; to an even simpler sort of still life painting in the 1970s and early 1980s.

The most remarkable thing about his career is how clearly it divides into three distinct phases: he started as an abstract artist in the late 1940s and early «50s, was enormously celebrated even in his twenties, and at the height of his success he then moved into figuration in 1955 following a move to Berkeley, California.

As opposed to the stark and direct tone of her earlier works, which were short and easily summarizable documentations of performance stunts, the films from this subsequent phase are ruminative and essayistic, and channel Chang's penchant for performative bizarrerie into intricate, large - scale meditations on a place or theme.

By the early 1960s, after he had moved from Paris to New York, Bluhm was already into the second phase of his career.