Sentences with phrase «into embryonic»

But researchers did know the genetic mutation that induced it, so Capecchi inserted that mutation into the embryonic stem cells of mice, then coaxed those cells into becoming embryos.
The positioning of the cells controls their genetic program and their differentiation into embryonic or extra-embryonic tissues.
The factors caused the differentiated stem cells to go into an embryonic - stem - cell - like state.
She argues that early research into embryonic stem cells have shown them to be largely unhelpful, while research using adult stem cells has cured or improved the outcome for such diseases as lupus and multiple sclerosis.
The idea of reprogramming a cell from adult tissue into an embryonic - like, pluripotent cell existed long before the creation of iPSCs.
The idea of reprogramming a cell from adult tissue into an embryonic - like cell existed long before the creation of iPS cells.
However, one line with 4 % carryover showed a wide drift when converted into an embryonic stem cell (hES) line, with some clones eventually having around 50 % of the original mitochondrial type.
iPSCs are cells that can be take from adult tissue and «reprogrammed» into embryonic stem cell (ESC)- like cells.
April 2012 - New research: Illuminating embryonic stem cells Collaboration between two EU funded projects «Heroic» and «EuroSyStem», has provided new insights into embryonic stem cells The teams used next generation sequencing technology to examine two key properties of the cells that influence their identity and behaviour: gene expression and gene regulation.
A second method involves introducing the transgenic DNA into embryonic stem cells (ES cells) derived from a mouse embryo at the very early stages of development.
It has recently been demonstrated that mouse and human fibroblasts can be reprogrammed into an embryonic stem cell - like state by introducing combinations of four transcription factors.
• In March, a University of Wisconsin team reprogrammed skin fibroblasts into embryonic stem cells without incorporating the viral or other foreign DNA that can lead to complications like cancer.
The researchers did this by injecting the cells into embryonic pancreatic tissue taken from mice engineered to lack neurogenin 3.
«Researchers are just now figuring out how adult somatic cells such as skin cells can be turned into embryonic stem cells.
Other researchers had successfully used a similar process to turn skin cells into embryonic - like cells called induced pluripotent stem cells, and then grow those iPS cells into nerve cells, but Wernig's lab was the first to convert skin cells directly into nerve cells without the intermediate iPS cell step.
The zebrafish is used as a model organism for research into the embryonic development of vertebrates.
Best known for his Superman films, Reeve had long advocated research into embryonic stem cells to repair the kind of spinal cord injury that left him paralyzed from the neck down after a horseback riding accident 10 years ago.
Three teams of scientists reported earlier this year that they had directly reprogrammed adult mouse skin cells into embryonic cells, although the process involved viruses and cancer - causing genes.
It is possible to force human skin cells to turn back into embryonic stem cells in the lab, but this doesn't seem to be something we are able to achieve without intervention.
But when physiologist H. Lee Sweeney of the University of Pennsylvania School of Medicine in Philadelphia and his colleagues put this faulty gene into embryonic quail muscle cells growing in lab dishes, the cells made a shortened version of the protein and incorporated it into their contractile machinery.
Scientists use OCT4 protein to reprogram adult cells into embryonic - like cells, an indication that it is involved in early development (SN: 11/24/07, p. 323).
They first inserted each enhancer into embryonic mice to learn whether it really did turn genes on.
The world's first chimeric monkeys were created in a laboratory last year, and they offer surprising new insights into embryonic stem cell therapy: One reason for often - poor treatment outcomes may be that we're using embryos that are, strangely, just too old.
«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.
Researchers remove these mechanically and, with some luck, can nurture them into an embryonic stem cell line that lives in perpetuity in the laboratory.
«We think that differentiation is a way that opens some doors and makes it easier for nuclear transfer programming to go back into embryonic stem cells.»
The observations add weight to the theory that transforming an adult cell's DNA into an embryonic state is a gradual reprogramming process, Hochedlinger says.
Jeanne Lawrence at the University of Massachusetts Medical School in Worcester took skin cells from men with the condition and «rewound» them into an embryonic state.
But to convert adult cells into embryonic - like cells means genetic reprogramming, for example with a virus, and the reprogrammed cells do not yet match embryonic stem cells.
The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.
Meet GloFish, the world's first genetically engineered pets — tropical zebra danios that fluoresce red thanks to a gene scientists transplanted into their embryonic DNA.
To turn one cell into another you usually need to first rewind them into embryonic - like stem cells.
The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.
Such a single - step conversion of an adult cell into an embryonic stem cell entirely avoids the question of whether an embryo has been created, since the cell produced by ANT - OAR never exhibits any of the properties of a single - cell embryo.
Thus the only difference between totipotent and pluripotent cells is that totipotent cells divide and differentiate into both embryonic stem cells and trophoblast cells.

Not exact matches

Some startups come into an incubator with an embryonic idea.
research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases such as Parkinson's, «stem - cells» has become synonymous with «embryonic stem - cells» in the public imagination.
The cell nuclei are removed from both sets of embryonic cells, as shown in the diagram, the donor's nuclei and the remains of the parents» embryo are destroyed and the parents» nuclei are then inserted into the donor or «host» embryo, still containing its healthy mitochondria.
Embryonic cells are pluripotent, having the full genetic code enabling them to become any type of cell; they differentiate into particular cells in their later development.
In our day it has been thrust into the realm of immediate urgency by advances in embryonic stem cell and cloning technologies.
For this reason, Evans counsels Christians to avoid the «embryonic life» narrative, which holds innocent human life to be inviolable from conception to natural death, because invoking the value of unborn life pushes people into pugilistic abortion - rights corners.
The idea of development seems to have come from biology, where it is used in reference to the process of evolution from a previous and lower (e.g., embryonic) stage to a later, more complex or more perfect one; this development can involve differentiation into individual organisms and their subsequent histories.
I have decided to break this topic down into 3 parts: How to Incubate Chicken Eggs with Kids, Stages of Embryonic Development and Activities to do while Incubating, and finally The Hatch and Going Home.
Your baby is now out of the embryonic period and into the fetal period.
As the tin pot dictators of the world eagerly await the opportunity to introduce their own «statutory underpinning» to shackle the media holding them to account, we can but only hope that the Lords will take the opportunity to ensure that small organisations, local micro-newspapers and embryonic blogger sites are not cast into the same chaos as the large newspapers will imminently face.
Instead, after several days, researchers harvest embryonic stem cells, which theoretically can develop into any type of cell and, according to many researchers, may someday be used to treat neurodegenerative diseases or other conditions.
To make the HSCs, the Harvard group used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.
Da Cruz and his team grew replacement RPE cells from human embryonic stem cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.
A recent federal court injunction based on a congressional budget amendment passed years before the first human embryonic stem cells were isolated has thrown many of the field's ongoing projects into limbo
Ten years ago, the team at Advanced Cell Technology announced that it had successfully converted human embryonic stem cells into retinal pigment epithelial cells.
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