Sentences with phrase «into embryonic state»

The observations add weight to the theory that transforming an adult cell's DNA into an embryonic state is a gradual reprogramming process, Hochedlinger says.

Jeanne Lawrence at the University of Massachusetts Medical School in Worcester took skin cells from men with the condition and «rewound» them into an embryonic state.

The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.

Not exact matches

To make the HSCs, the Harvard group used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

Semenza says methylation leads to the destruction of NANOG's mRNA so that no protein is made, which in turn causes the embryonic stem cells to abandon their stem cell state and mature into different cell types.

- Our results provide new insights into the mechanisms of how POLR3G gene regulates stem cell state, which in turn sheds light on the complex mechanisms with which human embryonic stem cells both self - renew and maintain the ability to differentiate.

In September California's Democratic governor, Gray Davis, crystallized the politics by signing the first state legislation permitting research on the embryonic cells, the master cells that can morph into any tissue in the body.

iPSCs are cells that have been genetically reprogrammed to an embryonic stem - cell - like state, meaning that they can differentiate into virtually any of the body's different cell types.

Human embryonic stem cells can exist in two different states that are termed naïve (the ground state) and primed (the state before differentiation into a specialised cell).

So this language in effect means alterations of embryonic cells can not be done in the United States if there is any intent to treat a human being, including implantation of an altered embryo into a woman's uterus.

It has recently been demonstrated that mouse and human fibroblasts can be reprogrammed into an embryonic stem cell - like state by introducing combinations of four transcription factors.

Now researchers led by the Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute have managed to induce a ground state by rewiring the genetic circuitry in human embryonic stem (ES) cells and in adult cells that have been induced into a pluripotent state.

Something about the environment of the egg again turned on all of the genes in what had been a differentiated nucleus, reprogramming the adult DNA to its embryonic state, and the newly pluripotent cell was able to grow into a tadpole.

Genetic modifications in skin cells (above) induced the cells into what scientists call a pluripotent state — a condition that is essentially the same as that of embryonic stem cells.

The factors caused the differentiated stem cells to go into an embryonic - stem - cell - like state.

Stewart discovered that the histone modifications that poise embryonic stem cell - specific genes for activation are also found on the histones near genes involved in regeneration, putting them into a ready - to - go state.