Sentences with phrase «into gene families»

The report in Nature provides new insights into gene families that are key to the malting process.

Not exact matches

In this special section of Science, expert contributors retrace the long and tortuous path leading to the mapping and identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activity.

To build a family tree for the orchids, the scientists sequenced genes in the green structures, called chloroplasts, in which plants transform solar energy into sugar.

This placed them in a new family, meaning it was beneficial to care for their own children at first (because they were more genetically related to them than they were to the rest of the family) and to care for their grandchildren later (when more of their genes made it into the family group).

The system relies on admixture — a genetic principle that argues that when a family migrates across a geographic barrier into a new location, they start mating with the locals; new traits start blending into their gene pool, and this genetic diversity provides a ruler for gauging the distance from home.

Another newly discovered family of genes makes compounds called uncoupling proteins, which allow people to convert excess fat into heat instead of storing it.

Biologists building family trees are likely being misled into suggesting that some organisms are closely related because genes and proteins are similar due to convergence, and not because the organisms had a recent common ancestor.

Optogenetics works by inserting the gene of a light - sensitive protein into live neurons, from a single cell to an entire family of them.

The vector is a self - inactivating lentivirus — a member of a family of viruses that can insert genes into mammalian cells and drive expression of those genes — that has been engineered to avoid triggering the development of leukemia, a complication seen in previous gene therapy trials for immunodeficiency syndromes, including WAS.

deCODE was able to narrow the location of the gene to a small chromosomal region, utilizing the genotypes of 2700 volunteer patients and relatives grouped into 200 families from across Iceland.

Failure to do this will render patients and families vulnerable, and risk bringing the wider field of gene transfer for serious diseases into disrepute.»

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

Furthermore, recombination between duplicated sequences introduces structural variation into the human genome and facilitates the formation of clustered gene families.

Since each bacterium's genome contains thousands of genes and each gene can express a protein, this technique made it possible to translate the reconstructed DNA of the microbial community into hundreds of thousands of proteins, which are then grouped into about 10,000 protein families.

Whilst a number of genes have been identified previously from investigation of families with Mendelian inheritance patterns, sequencing the DNA from large cohorts of individuals with congenital heart disease is now providing fresh insights into the genetics of these conditions.

The site has expanded rapidly and now has 15 million members - some 50 % of the adult population with access to the Internet - after moving into areas such as Genes Reunited, a site that allows people to trace their family tree.

The family values encoded into the Cayman genes since the very beginning are evident.

Nicki provides unique insight into being part of a large Italian - American family afflicted with the BRCA2 gene, and shares poignant stories about her mother and aunts who faced breast and ovarian cancer with extraordinary grace and courage.

Sonia Alice Gechtoff was born on Sept. 25, 1926, in Philadelphia, into a family with art in its genes.

Researchers at the University of British Columbia and the Child & Family Research Institute have shown that parental stress during their children's early years can leave an imprint on their sons» or daughters» genes — an imprint that lasts into adolescence and may affect how these genes are expressed later in life.

On Sept. 12, Toronto family lawyer Gene C. Colman will share his insights into the various types of alienation that grandparents may face.