Sentences with phrase «into gene products»

Not exact matches

Nusinersen and similar compounds being developed for spinal muscular atrophy focus on increasing or making more of the SMN gene product that gets converted into usable protein.

She is identifying the enzymes in these natural products to find the genes responsible so that they can be introduced into other plants.

Companies and academic labs that offer genetic testing can now incorporate previously patented genes into their products.

Since the gene product of YME1 is a potent suppressor of mitochondrial DNA migration into the genome of the yeast Saccharomyces cerevisiae, Tiwari and Singh investigated the human homologue of the YME1 gene, called YME1L1.

When human YME1L1 was introduced into yeast with the mutated YME1, the human gene product partially rescued the YME1 mutation, preventing migration of mitochondrial DNA into the nucleus.

The latter are more easily accessible to the cellular machinery that translates genes into their protein products.

Because this approach silences genes but does not introduce heritable changes into the genome, it may not be regulated as a GM product.

Then, to test the notion that a CAG repeat could cause this nuclear clumping, the team inserted a shortened MJD gene containing a long CAG repeat (78 CAGs) into cultured cells and watched the protein product migrate into the nucleus, aggregate there, and recruit the normal MJD protein into a tangle.

PARTICLE acts in three different ways to prevent expression of the MAT2A gene: 1) by winding around the MAT2A gene to create a DNA: RNA triple helix structure locking down the MAT2A gene promoter, 2) by binding the messenger RNA product of the MAT2A gene and preventing it being used for MAT2A protein synthesis and 3) transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected from the cell.

Informally called jumping genes, these bits of DNA can replicate and insert themselves into other regions of the genome, where they either lie silent, doing nothing; start churning out their own genetic products; or alter the activity of their neighboring genes.

As a prelude to introducing genes whose products would be therapeutically useful in cancer, the researchers say they have successfully introduced a harmless gene from bacteria into TILs without affecting the behaviour of the cells (Proceedings of the National Academy of Sciences, vol 87, p 473).

They modernized the factory by updating the carboxysome, a particularly complex BMC that requires a series of protein - protein interactions involving at least six gene products to form a metabolic core that takes CO2 out of the atmosphere and converts it into sugar.

Through its population - based approach and three main business units providing disease - gene and drug target identification, database services and informatics tools, deCODE is turning raw genomics data into products and services for the healthcare industry.

(The eukarya, thought to be descended from the archaea, rely on archaean - type genes to manage their DNA and to translate its genetic information into protein products.)

This approach enables us to leapfrog over several years of drug discovery and development and to go straight into information - rich trials, accelerating the application in the clinic of our gene discoveries and generating product - driven value for the company,» said Kari Stefansson, CEO of deCODE.

PPI does not introduce any foreign genes into its products; rather it regulates the plant's own genes to increase or decrease expression of the genes responsible for key traits.

We entered into an agreement with Bayer to research, develop and commercialize AAV gene therapy products for treatment of hemophilia A.

Students can perform RNAi «from scratch» using bioinformatics to develop PCR primers for a target gene, then cloning the amplified product into an RNAi feeding vector, and finally observing the phenotype of treated worms.

With its uniquely comprehensive population data, deCODE is turning research on the genetic causes of common diseases into a growing range of products and services — in gene discovery, pharmaceuticals, DNA - based diagnostics, pharmacogenomics, in silico discovery tools, bioinformatics and medical decision support systems.

Sigma - Aldrich ® and the Institute of Molecular Genetics, Czech Center for Phenogenomics, Establish CRISPR Core Lab Collaboration ST. LOUIS, Jan. 29, 2015 / PRNewswire / — Sigma - Aldrich Corporation's (NASDAQ: SIAL) Research business unit, which supports scientific research by supplying products, services and solutions, today announced it has entered into a new gene editing collaboration with the Czech Center

They can do this by combining genes from many different organisms, or even by designing new ways to translate genetic sequences of genes into protein products.

Ultimately, we aim to reveal the key species (cultured and uncultivated) involved in dental caries and provide new insights into specific genes / domains, gene products, and metabolic pathways that define the synergistic and competitive contributions to health and disease in this complex microbial community.

With its uniquely comprehensive population data, deCODE is turning research on the genetic causes of common diseases into a growing pipeline of products and services — in pharmaceuticals, gene and drug discovery, DNA - based diagnostics, pharmacogenomics, bioinformatics, and clinical trials.

We are also developing a unique method for guiding the products of these nuclear encoded mitochondrial genes back into the mitochondria, where they can then properly function.

With Monsanto's patented genes being inserted into roughly 95 percent of all soybeans and 80 percent of all corn grown in the U.S., the company has also used its wide reach to control the ability of new biotech firms to get wide distribution for their products, including big players in the food industry which have made an entire country falsely believe that these are health foods.

The product of the MDR1 gene, P - glycoprotein, is a large ATP - dependent transmembrane protein transporter found in the blood - brain barrier among other tissues.22 P - glycoprotein pumps substrates (e.g. ivermectin and loperamide) within the brain back into the blood.

They are a big product of their genetics - Mama Gem's genes live strong in these pups — and we have worked and remaining working hard to guide plus develop this litter into the Best Dogs they can be.

According to Yahoo News, «Monsanto's patented genes are being inserted into roughly 95 percent of all soybeans and 80 percent of all corn grown in the U.S., the company also is using its wide reach to control the ability of new biotech firms to get wide distribution for their products.»