Sentences with phrase «into haplotypes»
200/3: 30 Imputing genotypes of the Haplotype Reference Consortium into the haplotypes of a large case control study of age - related macular degeneration.
http://www.ashg.org/ Not exact matches
Apart from a few private Northern European haplotypes, all modern horse breeds included in the study clustered into a roughly 700 - year - old haplogroup, transmitted to Europe by the import of Oriental stallions, they report.
The D1 haplotype likely developed after early humans moved into the area from elsewhere in Asia.
This requires the development of powerful bioinformatic approaches that allow prediction of haplotypes from numerous variants, and the classification of haplotypes into functionally related categories, in order to identify those specific sequence variants, or combinations of variants, associated with the disease phenotype.
These patterns are known as haplotypes, and sets of similar haplotypes are organized into haplogroups.
Analysis of an archaic genome sequence indicated that the risk haplotype introgressed into modern humans via admixture with Neanderthals.
As a demonstration, we use the gPBWT to quickly count the number of haplotypes consistent with random walks in a genome graph, and with the paths taken by mapped reads; results suggest that haplotype consistency information can be practically incorporated into graph - based read mappers.
Results: BCFtools / csq is a fast program for haplotype - aware consequence calling which can take into account known phase.
The graph shows the number of haplotypes found in a survey of each breed, separated into Class I and Class II DLA.
However, once you start to introduce other breeds into a dog, these haplotypes actually start to break up.
Purebred dogs were also categorized into one of the 11 groupings based upon haplotype sharing as defined in Wayne and VonHoldt (2012)[14](n = 55,353): ancient and spitz (n = 2946), herding (n = 4579), mastiff - like (n = 5548), retriever (n = 18,347), scent hounds (n = 3742), sight hounds (n = 761), small terriers (n = 2534), spaniels (n = 4315), toy (n = 5542), working dogs 1 (poodles and Havanese; n = 1923), and working dogs 2 (n = 5116)(Additional file 1: Table S1 and Additional file 2: Table S2).
Standard poodles are in the AKC non-sporting group but in the working dog 1 haplotype association scheme, Havanese are in the AKC toy group yet are categorized as haplotype working dog 1, and the AKC sporting group includes retriever and spaniel breeds while the haplotype sharing approach splits those into two distinct groups.