Sentences with phrase «into human cells without»

After that was settled, gene therapists still had to find a suitable virus, or vector, to carry replacement genes into human cells without inciting a damaging or deadly immune response.

Not exact matches

Using viral gene insertion and regulatory proteins, researchers turned adult human skin cells directly into adult human blood cells, without first returning them to a fully pluripotent state.

To see whether this also applies to humans, the team engineered stem cells from people with and without Down's syndrome and injected them into mice.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

They then tested the behavior of human tumor cells with and without HOXA5 by injecting those cells into the mammary fat pad of mice.

It is possible to force human skin cells to turn back into embryonic stem cells in the lab, but this doesn't seem to be something we are able to achieve without intervention.

In an advance that could solve many of the ethical and technical issues involved in stem cell research, two groups of scientists have independently converted human skin cells directly into stem cells without creating or destroying embryos.

Another team, from Stanford University, converted human skin cells directly into neurons without first stopping at the stem cell stage, potentially making the process more efficient.

The 2012 platform also repeats previous calls for expanding federal funding «for the stem - cell research that now offers the greatest hope for many afflictions — with adult stem cells, umbilical cord blood, and cells reprogrammed into pluripotent stem cells — without the destruction of embryonic human life.»

Estes, who works with virologist Jeffrey Lifson, has also developed a DNAscope to visualize this HIV DNA — called the provirus — which becomes integrated into human cells and can persist for decades without being attacked by the immune system or antiretroviral (ARV) drugs.

The researchers then injected AAV2 into human breast cancer cell line - derived tumors in mice without functioning immune systems.

The industry or Institutes still try to do the same procedure without realizing, better accepting that stem cells are natural cells in a human body having a natural capability to home into problem areas of the body and to start their natural regeneration activity.

Several recent studies have demonstrated that human iPSCs can be generated without permanent integration of genetic factors into the reprogrammed cell chromatin [7], [8], [20]--[22].

One study presented in the journal — from a group led by Patrick Singleton, PhD, assistant professor of medicine at the University of Chicago Medicine — shows how opioids already present in the body can enhance the malignant tendencies of human lung cancer cells transplanted into mice, even without the addition of morphine.

They've been at it for a while, but scientists finally figured out how to delete disease - causing genetic code from single - celled human embryos — without any glitches — that were able to grow into disease - free multicellular embryos.

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Meanwhile, Dr. Mick Bhatia's group at the Stem Cell and Cancer Research Institute at McMaster University found a way to make human skin cells sing «Any Way You Want Me,» turning directly into blood cells without a pluripotent cell step in betwCell and Cancer Research Institute at McMaster University found a way to make human skin cells sing «Any Way You Want Me,» turning directly into blood cells without a pluripotent cell step in betwcell step in between.