Sentences with phrase «into human genome»

By one estimate, the federal government's $ 3.8 billion investment into the Human Genome Project has netted $ 796 billion in economic benefits, including 310,000 jobs and $ 244 billion in personal income.

Furthermore, recombination between duplicated sequences introduces structural variation into the human genome and facilitates the formation of clustered gene families.

He says HGS was getting «diminishing returns» from its investment in TIGR since Venter had steered his outfit into sequencing organisms of little medical importance, and into human genome sequencing, also of limited value for a company like HGS that is interested in genes as drug targets (not untranslated DNA that makes up most of the genome).

«New insight into the human genome through the lens of evolution.»

James Watson, Nobel prizewinner and former head of the American national research effort into the human genome, is one of the most vocal opponents of DNA patenting.

Despite confusion over how grants will be awarded and how ENCODE will proceed, participants were thrilled by the project — the first opportunity, they say, to dig deep into the human genome.

Once transferred into the human genome, however, these alleles became subject to natural selection, which was more effective in the larger human populations and has removed these gene variants over time.

But Sandmeyer hopes to use the new findings to modify retroviruses so that they can be safely integrated into the human genome.

In less than 1 percent of all adults, the virus can also quietly slip its own DNA into the human genome — making it possible for mothers and fathers to pass HHV - 6 to their offspring if these insertions are present in their eggs or sperm.

Not exact matches

Gilliland notes private company Solara bested the government - funded Human Genome Project by hitting important milestones first, and Elon Musk's SpaceX found a way to send rockets into space for a fifth the cost of a NASA launch.

The Greenwich, Connecticut - based hedge fund allegedly received illegal tips into negative news about Human Genome Sciences Inc HGSI.O, according to a criminal complaint and sources close to the matter.

The human Genome Initiative, begun modestly in 1988, will expand to a $ 200 million - a-year project by 1993 and continue into the next century.

Over eons, pieces of mitochondrial DNA have naturally inserted into eukaryotic genomes; at birth, for example, humans have between 755 and 1,155 germline mitochondrial DNA inserts that have been passed on through generations.

Since the gene product of YME1 is a potent suppressor of mitochondrial DNA migration into the genome of the yeast Saccharomyces cerevisiae, Tiwari and Singh investigated the human homologue of the YME1 gene, called YME1L1.

«If you don't use as close to the total physiological system that you can, you're likely to run into troubles,» like being surprised by side effects later on in clinical trials, says William Haseltine, founder and former chairman and CEO of Rockville, Md. — based Human Genome Sciences.

«The experience in the human genome project was that 25 % to 30 % of every project's budget went into informatics.

The analysis revealed that the human genome is organized into large pieces of low or high epigenetic stochasticity, and that these regions correspond to areas of chromosomes that are structurally different in the cell nucleus.

The National Institutes of Health and the Department of Energy held a conference in 2001 to celebrate 10 years of conducting research on the ethical, legal, and social implications of the Human Genome Project, as we reported in our story «A Decade of ELSI Research»: Embracing the Past and Gazing into the Future.

James Watson, for those of you who are reading this magazine by accident, won a Nobel Prize in 1962 for figuring out the structure of DNA, went on to head the Human Genome Project, and then talked himself into trouble and out of a job last year when, in an interview with The Sunday Times of London, he made one of the more outlandishly racist remarks in history.

Jeffrey Trent, an official at the National Human Genome Research Institute who monitored the NIH's inquiry into this case, says the Tribune's report is «accurate.»

The sequencing of genomes of 48 bird species explains the evolutionary roots of vocalization and could offer insight into human speech disorders

Obtaining it from living humans is not difficult, but it's a formidable challenge to extract and sequence genome - wide aDNA, which can degrade into fragments, undergo chemical reactions that change its code, and be contaminated by modern DNA.

Besides knocking out PERVs, which is relatively easy, making organ - donor pigs requires inserting large chunks of human DNA into the pig genome.

Although researchers do not yet know the biological significance of these discoveries, they say that fully cataloguing the genome may help them understand how genetic variations affect the risk of contracting diseases such as cancer as well as how humans grow from a single - celled embryo into an adult.

Around 75 per cent of the supposed functionless DNA in the human genome is transcribed into so - called non-coding RNAs (ribonucleic acid).

By comparing our genetic make - up to the genomes of mice, chimps and a menagerie of other species (rats, chickens, dogs, pufferfish, the microscopic worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster and many bacteria), scientists have learned a great deal about how genes evolve over time, and gained insights into human diseases.

Last spring researchers in China announced they used CRISPR to alter the genomes of nonviable human embryos which could not develop into babies.

«This study gives deep new insights into the life of a parasitic fluke in the human bile duct, and was enabled by the development of an exciting new genome assembly tool called OPERA - LG in our lab.

With more than 800 members in the human genome, GPCRs are the largest family of proteins involved in decoding signals as they come into the cell and then adapt the cell's function in response.

«Mapping the genome jungle: Unique animal traits could offer insight into human disease.»

As when he worked on the human genome, Venter is relying on a radical technique called shotgun sequencing: He chops up vast amounts of DNA into tiny pieces and then uses sophisticated computer analyzers to piece them back together into intelligible genes and chromosomes.

The new study shows that the synthetic compound is capable of inhibiting the activities of several DNA - processing enzymes, including the «integrase» used by the Human Immunodeficiency Virus (HIV) to insert its genome into that of its host cell.

The partitioning of humans into biological races was permissible when the knowledge of our genetic inheritance was based on less than 0.1 percent of the human genome.

Yet the unassuming fossil made it out of Denisova Cave in Siberia's Altai Mountains and into the Max Planck Institute's ancient DNA laboratory in Leipzig, Germany, where in 2010 it yielded a complete genome of a previously unknown type of human.

As scientists race to decode genomes — not just of humans but of bacteria, yeast, chimps, dogs, whales and plants — the number of DNA sequences available for analysis has grown 40,000-fold in the past 20 years, providing unprecedented insight into billions of years of species evolution.

I moved to the NIH in 1993 to take on this role of directing what was then called the Center (and is now called the Institute) of Human Genome Research, stepping into the shoes of Jim Watson.

The mouse genome is sometimes described as the human genome chopped into 150 pieces and put back in a different order along the mouse's 21 chromosomes.

HIV - 1 integrates its own genome into the genome of human immune system cells known as CD4 + T cells, hijacking their cellular machinery to make more copies of itself.

When researchers sequenced the chimpanzee genome in 2005, the biggest difference between it and the human genome was the extinct PtERV1 retrovirus, which inserted its DNA into the cells it infected like HIV does today.

Global: The Future of Genetics — Career Opportunities for Young Scientists Southern - European Editor Elisabeth Pain peeks into the new career avenues the sequencing of the human genome has opened, in academia and industry, and finds out what skills are needed to work in this field.

In the past decade innovation has taken researchers from sequencing the human genome, in 2001, to synthetically creating a bacteriophage in 2003, to just three years ago, turning one type of bacteria into another by genome transplantation.

An international group of 11 organizations with genetics expertise has issued a policy statement on germline genome editing in humans, which recommends against genome editing that culminates in human pregnancy; supports publicly funded, in vitro research into its potential clinical applications; and outlines scientific and societal steps necessary before implementation of such clinical applications is considered.

Now imagine a future where a successor to Venter is able to digitally reconstruct a set of the best possible sequences of human genomes and incorporate them, in pieces, into bacteria that could autonomously reproduce the sequences.

They could turn back the clock of evolution: Church has proposed a way of altering the elephant genome until it is identical to a woolly mammoth's, or turning a human's DNA into a Neanderthal's.

Yet the discovery shows that with ever - cheaper genetic sequencing and faster computers, it is possible to recover a full nuclear DNA sequence from an ancient human, even when the genome is broken into tiny fragments.

«For 15 years, an impressive amount of time and money poured into discovering the genomes of mammals, motivated by our drive to understand human evolution and to look for cures for disease.

Rewiring gene activity in humans happened, in part, when transposons inserted themselves into the genomes of human ancestors after the split from chimpanzees, he reported last year in Genome Biology and Evolution.

Now, the fungus» genome sequence, released today, could provide new insights into ecology, evolution, and human health.

And researchers at Stanford University School of Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.

COLD SPRING HARBOR, NEW YORK — A dozen scientific teams have endorsed an international plan to complete a «working draft» of the human genome by the spring of 2000 and polish it into a «highly accurate» version by 2003.