Sentences with phrase «into human therapies»

Not exact matches

It is interesting to note in this context that family therapy broke out of purely intrapsychic relations into wider systems of relationships that characterize and condition us all; and now we see the more recent birth of «ecological» therapy, where the concern broadens to include human relationships to the fullest extent possible (see FFT 256ff.).

Of course, there is still a long way to go before this particular method will be tested on humans (it was tested on mice), and an even longer way to go before it'll be used in medical therapies (if it ever will translate into therapies), but one thing is becoming clear: We need not compromise our moral principles and rush into government - funded embryo - destructive research.

«These new insights into the complexities of epigenetic regulation are contributing to our basic understanding of this process in human health and disease and gives us new vision for how to go about targeting errors in DNA methylation with innovative drug therapies.»

The process of integrating naturally occurring cancers in dogs into the general studies of human cancer biology and therapy is known as comparative oncology.

It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.

GABA and related therapies would have to be tested in human clinical trials, a process that could take several years, the researchers said, noting that many treatments that work in mice do not always translate into effective human therapies.

For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.

Gene therapy can be used to neutralise harmful human genes, such as those that cause cancer, or to insert healthy copies of damaged genes into people with a genetic disease.

While each appeals to a different sort of person, they all tap into basic human needs and desires, so a new world religion would have a harmonious blend of them all: the euphoria and sensual trappings of a sacred party, the sympathy and soothing balms of therapy, the mysteries and revelations of an eternal journey and the nurturing, didactic atmosphere of a school.

Most gene - therapy trials use viruses to deliver genes to a patient's cells, and most of those viruses are retroviruses, which have the ability to neatly splice their genes — and the human gene they're carrying — into a cell's chromosomes.

«You'd still have to ration the therapy,» cautions Robert Hariri, chief researcher at Anthrogenesis in Cedar Knolls, New Jersey, which announced this year that it had morphed human placental stem cells into nerve, blood, cartilage, skin, and muscle cells.

The roadmap outlines future research directions toward the goal of enhancing human radioresistance, including upregulation of endogenous repair and radioprotective mechanisms, possible leeways into gene therapy in order to enhance radioresistance via the translation of exogenous and engineered DNA repair and radioprotective mechanisms, the substitution of organic molecules with fortified isoforms, the coordination of regenerative and ablative technologies, and methods of slowing metabolic activity while preserving cognitive function.

«The addition of osteocalcin as a metabolic regulator may one day lead to novel therapies, but we need to understand much better how it works and how it fits into physiology before such therapies can be attempted in humans,» says endocrinologist Mitch Lazar, director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania.

Ian Hindmarch, head of the Human Psychopharmacology Research Unit at the University of Surrey, thinks it is «cynical» to turn the normal process of ageing into a clinical condition deserving some kind of therapy.

The finding could fundamentally change how we look at human stem cell tech: If chimeric monkeys require totipotent cells before they can come into being, it stands to reason that human embryonic stem cell therapy might also require totipotent stem cells to render cures.

Stem cells obtained from human embryos seem to offer the best chance of new therapies, because unlike other stem cells they have the ability to morph into almost any type of tissue.

A fix for broken rat hearts Scientists this week successfully implanted human embryonic stem cells into rats that suffered heart attacks, coming a heartbeat closer to realizing the full potential of such therapy.

«The primary mission of the USC Neurorestoration Center is to take advantage of resources from our clinical programs to create unique opportunities to translate scientific discoveries, such as those of the Andersen Lab at Caltech, to human patients, ultimately turning transformative discoveries into effective therapies,» says center director Charles Y. Liu, professor of neurological surgery, neurology, and biomedical engineering at USC, who led the surgical implant procedure and the USC / Rancho Los Amigos team in the collaboration.

«We hope to determine how this pathway might translate into better stem cell therapies for human disease,» added Agrawal.

For the animal experiments, Savio Woo of the Center for Gene Therapy at Baylor College of Medicine in Houston and his colleagues first isolated liver cells from transgenic mice that produce the human protein a1 - antitrypsin in their livers, from where it is secreted into the blood.

«The introduction of mitochondria into damaged cells has beneficial effects on the health of cells and, in the long term, we believe that mesenchymal stem cells could even be engineered to create more effective therapies for lung disease in humans.»

In Britain, the regulations governing genetically modified organisms came into force in 1992, before the implications for gene therapy were appreciated, and in practice the law has not been applied strictly to humans.

That's a long way from it working in people, but because it seems a safe therapy, it could move quickly into human trials.

For the past 3 months, faculty and staff members at the University of Pennsylvania's Institute for Human Gene Therapy have been trying to understand why a relatively fit 18 - year - old with an inherited enzyme deficiency died on 17 September, 4 days after doctors at Penn injected a genetically altered virus into his liver.

Thus far, the Newcastle team has worked with abnormally fertilized human eggs that will not develop into viable embryos; the new money will allow them to use normal, leftover eggs from IVF therapy.

They then stitched the genes for these immunoadhesins into an adeno - associated virus (AAV), a «vector» used in human gene therapy experiments to deliver foreign DNA into the body's cells.

A collaboration of premier academic, medical and industry leaders across the globe, the New York Genome Center has as its goal to translate genomic research into the development of new treatments, therapies and therapeutics against human disease.

If we can't measure the positive effects of these candidate therapies, we can't hope to transition them into human subjects trials.

«ViaCyte was the first to differentiate human stem cells into glucose - responsive, insulin - producing cells, and now we are running the first and only clinical trials of stem cell - derived islet replacement therapies for type 1 diabetes,» said Paul Laikind, PhD, President and CEO of ViaCyte.

They encourage research aimed at translating laboratory discoveries about the brain and nervous system into diagnoses and therapies to improve human health.

«Our decision to procure these knockout mouse lines and data and make them available to the research community will yield tremendous benefits, both in the short and long terms,» said NIH Director Elias A. Zerhouni, M.D. «This trans - NIH initiative will place important mouse models into the hands of researchers, speeding advances in the understanding of human disease and the development of new therapies.

How would this development (and whatever drug or therapy they devise for humans) move from the lab and into trials, without it taking decades, like the author here proposes?

Human mesenchymal stem cells (hMSCs) are currently the most common adult stem cell type used for cell therapy applications due to their regenerative properties and ability to differentiate into multiple cell lineages (adipocyte, chondro ¬ cyte, and osteocyte).

At its conclusion, we will have a candidate gene therapy for AMD; however, such therapy will need to be tested for safety before being able to advance into humans.

The Cancer Center conducts paradigm - shifting, collaborative multidisciplinary basic research into the causes, prevention, and treatment of cancer, leading to new therapies that overcome cancer as a cause of human suffering and disease.

Leveraging Moderna's messenger RNA Therapeutics ™ platform, an entirely new in vivo drug modality that produces human proteins or antibodies inside patient cells, Onkaido plans to rapidly turn scientific innovation into cancer therapies that can make a real difference for patients.

If the results translate to humans, the researchers say, it could lead to new therapies for maintaining healthy brain function into old age.

After having initial success using CRISPR therapy with mice, he has moved on to inserting human stem cells into monkeys for his experiments.

The reprogramming of human somatic cells into induced pluripotent stem cells (iPSCs) offers tremendous potential for cell therapy, basic research, disease modeling, and drug development.

4/7/2008 From Bench to Bedside in One Year: Stem Cell Research Leads to Potential New Therapy for Rare Blood Disorder A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leuk... More...

The study of the genetic and molecular pathways underlying regeneration in these species provides insight into the dormant molecular pathways for regeneration in humans, raising the prospect therapies can be developed to trigger human regenerative capacity.

Two teams independently discover a way to turn ordinary human skins cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.

Lanza's dream of turning human embryonic stem cells into therapies for the sick and the suffering is taking a huge step closer to reality.

Memory & Cognitive Disorder Awards encourage research aimed at translating laboratory discoveries about the brain and nervous system into diagnoses and therapies to improve human health.

Two teams of scientists have independently discovered a way to turn ordinary human skin cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.

If successful, this may lead to therapies for humans in which a patient's stem cells will be reverted into iPSCs, then genetically repaired and transplanted back into the bone marrow of the same patient.

With the new center, we will be expanding upon our role as a global hub to help students and professionals maximize their potential, realize their career ambitions, contribute to the advancement of biomedical science and translate their ideas and discoveries into products, services and therapies that will benefit human health and well being.

«While this is promising, we have many steps to go to translate these discoveries from mice into a therapy for humans using this noninvasive technique,» Singer said during the press conference.

By studying them, we are beginning to gain insight into human disease — to understand why organs such as the heart can not repair themselves or why, as we age, the incidence of debilitating diseases such as cancer, heart disease and Alzheimer's increases so rapidly, and we are developing new therapies that will enhance our abilities to regenerate damaged tissues and prolong healthy lifespan.

Direct conversion or reprogramming of human postnatal cells into endothelial cells (ECs), bypassing stem or progenitor cell status, is crucial for regenerative medicine, cell therapy, and pathophysiological investigation but has remained largely unexplored.