Sentences with phrase «into huntingtin»

As expected, they found that the normal and extra-long genetic instructions were both translated into huntingtin proteins when they met up with a ribosome (the chef from our analogy above).

an organism that has had one of its genes altered, for example by adding a long CAG repeat into the huntingtin gene.

Not exact matches

«We think the mutant huntingtin is being released into the CSF from the very brain cells it is killing,» said Dr Edward Wild of UCL Institute of Neurology.

When caspases chopped off small peptides from the mutant region of huntingtin, they thought, the peptides accumulated into the abnormal globs seen in the neurons of Huntington's victims.

By placing aSyn and the huntingtin protein into the library separately and then monitoring each cell's reaction, they were able to deduce which genes are important for the cells to survive the toxic insult from aSyn, and which ones are needed to help the cells survive the huntingtin protein.

It acts as a caspase inhibitor, which means it could prevent the dangerous huntingtin protein from being broken into small enough fragments to enter the cell's nucleus and mess up the switching on and off of important genes.

Adding a tag called ubiquitin to the alpha synuclein prevents it sticking together into clumps (huntingtin does this too).