Sentences with phrase «into keratinocytes»

Meganuclease - mediated integration of two constructs aiming at monitoring the differentiation of hiPS cells into keratinocytes will be performed.

For the first set of experiments, first author Trond Aasen, Ph.D., a postdoctoral researcher at the Center of Regenerative Medicine in Barcelona, used viral vectors to slip the genes for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into keratinocytes cultured from human skin explants.

Starting with procedures other research teams had previously worked out to convert iPSCs into keratinocytes, Xu's team demonstrated that by carefully controlling the timing of the growth factors the cells received, they could force the iPSCs to generate large numbers of epithelial stem cells.

The scientists found that celecoxib directly increased stem cell differentiation into keratinocytes — skin cells required for wound healing.

Not exact matches

«We culture typical skin cell of the epidermis, such as human keratinocytes, in our dishes to form an artificial epidermis with all of its natural layers,» explained Sibylle Thude, the biologist who led the investigation into the accreditation.

One potential treatment involves injecting the wound with stem cells, which can change into other cell types, such as skin cells like keratinocytes, to help with the healing process.

This requires the activation of progenitor keratinocyte (PK) cells that turn into new follicles.

The top four images, from left to right, show Keratinocyte - derived neural crest stem cells turning into neurons as shown by typical neuronal morphology.

The researchers then successfully prodded what they call keratinocyte - derived iPS cells or KiPS cells to distinguish them from fibroblast - derived iPS cells into becoming all the cell types in the human body, including heart muscle cells and dopamine - producing neurons, which are affected by Parkinson's disease.