Sentences with phrase «into macrophages»

In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.

They are recruited to sites of injury or infection and there turn into macrophages (literally «large eaters») that ingest pathogens, infected cells, or cellular debris.

During a bacterial infection, monocytes penetrate the infected tissue where they differentiate / change into macrophages.

The particles delivered fragile but potent RNA molecules into macrophages, inflammatory cells that swarm into cardiac tissue after a heart attack.

Our general aim is to decipher at the molecular level how incoming HIV is sensed, how macrophages react to HIV, how HIV escapes this control and succeeds to replicate into macrophages.

Atherosclerosis is initiated by high plasma cholesterol leading to monocyte entry into the artery wall and differentiation into macrophages, which take up lipoprotein cholesterol to become lipid engorged foam cells.

Monocytes are a specific type of phagocytic cells which enter the damaged muscle fiber and transform into macrophages which also produce toxins which further destroy the damaged area.

Boris Brumshtein, Paul Salinas, Brian R Peterson, Victor Chan, Israel Silman, Joel L Sussman, Philip J Savickas, Gregory S Robinson, and Anthony H Futerman (2010) Characterization of gene - activated human acid - β - glucosidase: Crystal structure, glycan composition, and internalization into macrophages.

Upon infection or tissue damage, monocytes, one of the major groups of white blood cells, rapidly differentiate into macrophages.

The team looked at blood samples from more than 100 younger, healthy subjects as well as 61 older subjects and measured protein levels in monocytes — immune cells that can travel to various sites throughout the body, including the brain where they differentiate into macrophages, specialized for their new environment, in this case the central nervous system.

Making B - cells (B lymphocytes) express C / EBP transcription factors (blue) can cause them to differentiate into macrophages.