Sentences with phrase «into mature cell types»

Not exact matches

The project's goals were to explore and describe the range of epigenetic changes that take place in bone marrow as stem cells develop into different types of mature blood cell.

The team at the University's Medical Research Council Centre for Regenerative Medicine were surprised to find the molecules can also boost direct conversions from one type of mature cell to another — including transforming skin cells into brain cells.

The molecules — called SMAD2 and SMAD3 — can enhance the efficiency of converting mature cells into induced pluripotent stem cells, which have the distinctive ability to become any type of cell found in the body.

Culled from embryos barely 4 or 5 days old, these cells are versatile shape - shifters that can mature into any type of cell in the body — a trait that's made them crucial to research.

Reproductive cells, such as an egg and sperm, join to form stem cells that can mature into any tissue type.

Semenza says methylation leads to the destruction of NANOG's mRNA so that no protein is made, which in turn causes the embryonic stem cells to abandon their stem cell state and mature into different cell types.

All stem cells are immature cells known for their ability to multiply indefinitely and give rise to progenitor cells that mature into specific cell types that populate the body's tissues during embryonic development.

Moving forward, he was able to place these taste stem cells in a culture dish and prompt them to grow into the different mature taste cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.

The researchers traced stem cells as they matured into motor neurons, which are the type of nerve cells that control muscle movement.

As «immature» somatic cells, stem cells can mature into different types of cells, thus making them responsible for the development of all the tissues and organs in the body.

Their stem cells, which can mature into any type of tissue, were isolated and cultured in a dish around dots of gel - like growth medium.

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

Although unequal division occurs among stem cells — allowing one daughter cell to remain a stem cell while the other matures into another cell type, such as a skin or muscle cell — the goal of a normal symmetric cell division is to generate identical daughter cells and increase cell number.

A promising type of therapy called differentiation therapy targets these malignant cells so that they can resume the process of differentiating into mature cells.

A study published October 18 in Biophysical Journal reveals that the softness of corneal cells indicates their potential for stem - like activity, including the ability to self - multiply and turn into different types of mature cells.

Loss of heterochromatin regulation has potential consequences for the long - term genetic stability of stem cells, and the ability of stem cells to mature into specialised cell types.

After implantation, the cells are expected to mature into the full complement of islet cells, including insulin - producing beta cells, offering a potential functional cure for patients with high - risk type 1 diabetes.

In medicine, pluripotent is an adjective used to describe a type of stem cell that can mature into any other type of cell in the body.

Scientists describe its stem cells as universal «blank slates,» because each can mature into any type of tissue.

Endoderm cells are a type of cell found in the early embryo, and which eventually mature into the body's major organs — including the pancreas, the home of β - cells.

They can mature into many types — sometimes any types — of cells that the body may need.

Stem cells from fat have the ability to mature into other types of specific cells, including muscle, bone and cartilage, but how many other types is still unknown.

The stem cells develop into one of three types of mature blood cells:

Endoderm cells are a type of cell found in the early embryo, and which eventually mature into the body's major organs — including the pancreas, the home of ß - cells.

This means these cells can mature into any other type.

At the heart of Clevers» work were adult stem cells, a type of cell that can replenish itself while also maintaining the ability to change into the many types of mature cells that a particular tissue or organ requires.

Surprisingly, by introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, ie immature cells that are able to develop into all types of cells in the body.

To build an in vitro model of the human glomerulus to probe deeper into its function and vulnerabilities to disease and drug toxicities, researchers have been attempting to engineer human stem cells — that in theory can give rise to any mature cell type — so that they form into functional podocytes.

The technique uses cells from a patient's skin to generate induced pluripotent stem cells (iPSCs), which are capable of developing into various types of mature tissues — including blood.

By turning on a single gene, researchers can prevent skin stem cells from maturing into the three types of adult skin cells — epidermal, sebaceous and hair cells.

The first scenario would preclude the possibility of changing one type of mature cell into another because the cell would no longer contain the genetic wherewithal to perform all possible functions.