In this reconstituted schematic, hematopoietic stem cells (HSC) transplanted in a mouse model of Friedreich's ataxia differentiate
into microglial cells (red) and transfer mitochondrial protein (green) to neurons (blue), preventing neurodegeneration.
Not exact matches
Building on the evidence that microglia were in play during injury, the researchers conducted tests in zebrafish with the specialized enzyme incorporated
into both rod
cells and
microglial cells, removing both
cell types to ask what role microglia play during regeneration.
Indeed, recent data demonstrate that when
microglial cells are removed from the brain and cultured in vitro, they rapidly transform
into something else.