Sentences with phrase «into microtubules»

«Our results indicate that TACC3's function completely depends on this interaction, so that mutations in the latter prevent chTOG from correctly incorporating into the microtubules,» states Montoya.

Building from two subunits, alpha and beta tubulin, this protein assembles into microtubules that play a vital role inside cells — giving structure, pushing or pulling other things around, or providing a track on which other molecules can pull themselves along.

Not exact matches

Unexpectedly, the team discovered a thick band of microtubules, a component of the cell's cytoskeleton, that extended from the axon of the neuron into the synaptic terminal and then looped around the interior periphery of the terminal.

After gathering into a big blob around the chromosomes, the many microtubule organizing centers then began to repel each other.

During mitosis, microtubules disassemble and reform into spindles that are used by the dividing cell to move chromosomes.

The findings suggest that these previously unknown microtubule structures provide a «roadway» for the transport of mitochondria crucial to maintain energy supplies into the synaptic terminals of these highly active neurons associated with vision.

«Zika virus infections cause a drastic perturbation of the cytoskeletal network, re-organizing both intermediate filaments and microtubules into a cage - like structure that surrounds the replication machinery.»

Microtubules even come into play on the outside of cells, forming into cilia and flagella that allow for cell movement.

Bandyopadhyay inserted the needle into a rat neuron to view the microtubule.

Tubulin, a flexible protein, assembles into a long chain to create microtubules.

The second is to add desensitisers such as potassium salts, which diffuse into the tooth via the microtubules and depolarise the nerve.

These units assemble themselves into chains, forming the microtubule.

«In addition to the new insights into plant cell microtubule organization, these observations of GCP - WD function will be of interest to scientists studying microtubules in animals, where GCP - WD has been challenging to observe it in action,» Ehrhardt added.

Somehow, the cell wrangles the growing microtubules, bringing them into clustered bundles that extend in common directions.

Before the cell can use microtubules for these and other essential functions, it must first organize them into carefully crafted bundles, which become the basis for three dimensional shapes.

They extracted cytoplasm from frog eggs, which contains dynein and all of the components needed to make spindles, added fluorescent protein and the chemotherapy drug Taxol to create and stabilize microtubules, and loaded the mixture into «the world's simplest microfluidic chamber.»

«If we can learn more about the interactions between the actin and microtubule systems, we could translate this knowledge into improved cotton fibers and trichome plant defense systems in crop species.

Microtubules can spontaneously self - organize, transforming from many singular components into one large cellular structure capable of performing specific tasks.

Now, researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have observed how microtubules and motor proteins assemble into macroscopic networks.

In order to segregate chromosomes into the two emerging cells, the spindle itself needs a bipolar structure, and so the microtubules must be sorted to align with the long pole - to - pole axis of the spindle.

If the movement is gradual, the microtubules will immediately slide back into place after the stretching stops, with no harm done.

When cells divide, a molecular motor called the microtubule spindle helps segregate chromosomes into the resulting daughter cells.

The atomic structure from the NIH team could be fit into the lower - resolution 3D EM image reconstruction to identify the regions of the protein that interacted with the microtubule surface.

A deeper look into the mechanism by which alpha - synuclein inhibits endocytosis revealed toxic effects of the over-assembly of microtubules.

We know the initial target and the mechanism... [But] in order to step into [the treatment] stage, we should probably work a little bit more to know by what mechanism the microtubules interfere with endocytosis.»

Upon expression in dividing cells, survivin is rapidly recruited to various aspects of the mitotic apparatus, the scaffolding of microtubules that serve to physically separate and sort the proper complement of chromosomes into each of the two new cells that result from mitosis.

Numerous biochemical and structural changes occur throughout the cell as the microtubule - based spindle assembles and attaches to the condensed chromosomes, segregates them, and signals to the cell cortex to induce cleavage into two daughter cells through an actin - based contraction.

The progressive diversification of the microtubule field into subdomains has created the need for a strong meeting that unifies the community and brings together researchers from different disciplines interested in microtubule research.

Furthermore, microtubules are the major constituents of the mitotic spindle, which mediates the orderly segregation of the replicated chromosome sets into the two daughter cells during cell division.