Sentences with phrase «into mouse lungs»

Then Shapiro and his colleagues injected elastin fragments directly into mouse lungs.

Not exact matches

Recently, NASA scientist Chiu - Wing Lam spritzed carbon nanotubes into the lungs of mice and found that they caused granulomas, nodules that are symptoms of toxicity.

«The virus penetrates more deeply into the lungs of obese mice, and the animals seem to have a more difficult time repairing the damage,» Schultz - Cherry said.

The samples were incubated to enrich for BMICs, then injected into the lungs, hearts and brains of mice.

A team from Cold Spring Harbor Laboratory in Long Island, N.Y., reports that it staved off full - blown metastasis in mice by preventing mini-tumors in the lungs from recruiting stem cells called endothelial progenitors, which assemble into blood vessels to nourish the malignancy.

• A Yale research team led by Diane Krause turned a single stem cell from the bone marrow of an adult mouse into lung, liver, intestinal, and skin cells for other mice.

To accelerate the process, scientists delivered the gel and clearing agents directly into the bloodstreams of dead mice, clearing their kidneys, hearts, lungs, and intestines within days and their entire brains and bodies within weeks.

In mice, when white blood cells in the lungs engulf spores of a common airborne fungus, these immune cells release an enzyme that sends the fungal cells into programmed cell death.

the team broke the virus down and inserted genes from the killer strain, one at a time, into a related but benign bird influenza virus that normally infects only the lungs of mice.

The team, lead by Professor Lester Kobzik at the Harvard University School of Public Health, introduced Streptococcus pneumoniae into the lungs of mice to mimic the inhalation of bacteria that occurs naturally as we breathe.

Massagué and colleagues took cells from a single patient, injected them into mice, and isolated the cells that spread and thrived in the lungs.

«Earlier studies have shown that vitamin E can help regulate the aging body's immune system, but our present research is the first study to demonstrate that dietary vitamin E regulates neutrophil entry into the lungs in mice, and so dramatically reduces inflammation, and helps fight off infection by this common type of bacteria,» said first author Elsa N. Bou Ghanem, Ph.D., postdoctoral scholar in the department of molecular biology and microbiology at Tufts University School of Medicine (TUSM).

Nearly all of the mice had the pneumonia bacteria spread from the lungs into their bloodstream, ultimately killing them.

The researchers used a modified virus to insert genetic mutations into cells lining the mice's lungs, causing the animals to develop tumors.

When they infused the cells intravenously into mice, they found that most of the cells gathered in the animals» lungs.

The experimental metastasis assay we detail here includes tail - vein injection of cancer cells into the mouse and determination of the resulting secondary organ colonization, primarily in the lung, 10 d post dosing.

In this study, human lung cancer cells with additional copies of the opioid receptor grew more than twice as fast as tumor cells that lacked extra receptors when transplanted into mice.

To do so, they injected melanoma cells into the bloodstream of normal or E2 mutant mice and monitored lung metastasis.

One study presented in the journal — from a group led by Patrick Singleton, PhD, assistant professor of medicine at the University of Chicago Medicine — shows how opioids already present in the body can enhance the malignant tendencies of human lung cancer cells transplanted into mice, even without the addition of morphine.

Finally, to determine whether LARP7 KD also results in an increase in breast cancer metastasis in vivo, the T47D control or shLARP7 - 2 cells were injected intravenously into the nude mice, and lung metastasis was examined 12 weeks later.