Mesenchymal stem cells, harvested from Guilkey's fat, and growth - encouraging morphogenetic protein - 2 (BMP - 2), were injected into holes drilled
into the scaffolds.
To this aim, the researchers incorporated molecules
into the scaffolds that are known as the major histocompatibility complex (MHC) and that presented small peptides derived from viral proteins to T cells.
Jim and Marilyn Walpole were visiting Toronto on a weekend bus tour for seniors when Jim stumbled and fell
into scaffolding, slitting his throat.
Delving into imprinting is also yielding insights
into the scaffolding of the genome, and the ways in which parents put a stamp on gene expression, influencing health and disease in their children.
While the 3D injectable scaffold is being tested in mice as a potential cancer vaccine, any combination of different antigens and drugs could be loaded
into the scaffold, meaning it could also be used to treat infectious diseases that may be resistant to conventional treatments.
A structure on the enzymes — a dockerin — allows the enzyme to plug
into the scaffolding mechanism.
«Most previous scaffolds have supported axon growth
into the scaffold but not out again.
Eight weeks after the Northwestern researchers implanted the hyperelastic bone, they found that new blood vessels had grown
into their scaffold — a necessary step to keep bone - forming tissue alive — and calcified bone started to form from the rats» existing stem cells.
In animal tissues and organs, cells lock
into a scaffold of collagen proteins that allows the cells to stick together and coordinate activities, such as tissue repair.
During fabrication, living cells can be integrated
into the scaffold, and its mechanical properties can be controlled to create a made - to - order patch of tissue.
An unidentified man jumped in the idling S550, attempted to make a U-turn, and crashed
into scaffolding for a building across the street from the convenience store.
Policymakers would be wise to coordinate these early childhood resources
into a scaffolding of developmental support for disadvantaged children and provide access to all in need.
Not exact matches
ReInnervate, a start - up in Durham, England, is developing a tiny, three - dimensional plastic
scaffolding on which human cells can be grown
into artificial tissue, and perhaps eventually
into replacements for organs.
With far fewer attachment points than
scaffolding discs, gumfoot discs allow the web to detach with ease and yank off the ground any prey that has walked
into it.
Flags hanging from a
scaffold, red smoke and a hell of a lot of noise let the opposing players know they were going
into the Lions» den and the Liverpool team knew we were right behind them on the streets.
He labored under sheets of plastic, swathed around a five - story
scaffold skeleton and the sculpture itself, that turned his workspace
into a 120 - degree steambath.
With a rope that can be tied to any
scaffold and an impressive maximum weight capacity, this swing will grow with your toddler well
into childhood.
Da Cruz and his team grew replacement RPE cells from human embryonic stem cells on a thin plastic
scaffold, before transplanting the tissue
into the back of each volunteer's eye.
In the early universe, astronomers believe, dark matter provided the gravitational
scaffolding on which ordinary matter coalesced and grew
into galaxies.
The team pumped around 50 million rat liver cells
into each of five bare
scaffolds, then incubated the organs in culture for two weeks.
To solve this problem, Smadar Cohen, a tissue engineer at Ben - Gurion University of the Negev in Beersheba, Israel, and colleagues seeded rat cardiac cells onto
scaffolds which they transplanted
into the omentums of eight rats.
In many ways, Pinker's book The Stuff of Thought: Language as a Window
Into Human Nature, which will be published this month, may be his most ambitious yet — an attempt to show that the entire range of human thought is built on the «
scaffolding» of a few core concepts that shape our understanding of the physical and social worlds and form the basis for the way we interpret reality.
Connecting those patches forces the
scaffold to fold
into a prescribed shape.
These results, along with imaging technologies that capture pathogens in the living host, form a «
scaffold» for future research
into Lyme disease, says Joseph Breen, bacteriology program officer at the National Institute of Allergy and Infectious Diseases, which funded the work.
Guided by the
scaffold pattern, the ensemble promptly organized itself
into elongated muscle strands, complete with onboard arteries and veins.
The researchers reported the natural inflammatory response when a foreign substance like a hydrogel is introduced
into a system and draws cells that secrete proteins involved in cellular infiltration,
scaffold degradation, vascularization and innervation.
The surgeon, John Itamura, had implanted an ECM
scaffold into the shoulder of a patient who returned eight weeks later in need of surgery for an unrelated problem.
For these animals the museum built temporary wooden
scaffolding into the dioramas to save fragile grasses and plants from being trampled, allowing conservators and taxidermists more freedom to work inside.
They grew these myoblasts by many folds and then put them
into a supportive 3 - D
scaffolding filled with a nourishing gel that allowed them to form aligned and functioning human muscle fibers.
The peptide molecules self - assemble
into long structures called nanofibers, which come together to form a molecular «
scaffold.»
Once the bio-ink adheres to the
scaffolding, it goes
into a bioreactor, an appliance like a rotisserie oven that keeps the cells warm and growing evenly.
The bio-ink, which stays at room temperature, is extruded during the 3D printing process and fills in gaps in the PLA
scaffolding, then cures
into a gel on the heated build plate of the MakerBot Replicator 2X.
«What the
scaffolding proteins do is convert that short memory
into something that can last for hours.»
Whereas the team's model proved that the presence of more
scaffolding proteins available at the far downstream end of the neuron (and
into the synapse) to AMPA receptors increased during LTP, they found the opposite condition for LDP.
Engineered RNA modules were assembled
into discrete, one - dimensional, and two - dimensional
scaffolds with distinct protein - docking sites and used to control the spatial organization of a hydrogen - producing pathway.
With as many as a thousand tubes fitting
into each cell, the tubular
scaffold can be used to increase the bacteria's efficiency to make commodities and provide the foundation for a new era of cellular protein engineering.
The team then carefully inserted mouse follicles — spherical structures containing a growing egg surrounded by hormone - producing cells —
into these «
scaffolds.»
Histones are proteins that serve as a
scaffold for coiling up the DNA
into the tight space of the nucleus.
Particles like silver iodide can provide a
scaffold on which water molecules can align themselves
into a crystalline structure or, in other words, freeze.
The rods spontaneously assemble at the vaccination site to form a three - dimensional
scaffold, like pouring a box of matchsticks
into a pile on a table.
Just like raising a building requires
scaffolding be erected first, cells use biochemical
scaffolding machinery to reassemble copied genomic fragments back
into chromosomes.
He then seeded the cells on a polymer
scaffolding, infused them with apatite (a mineral component of bone), and injected the mix
into small holes he had drilled
into the animals» skulls.
Some examples of these nanoscale protein materials are
scaffolds to anchor cellular activities, molecular motors to drive physiological events, and capsules for delivering viruses
into host cells.
«We expect that a patient's central nervous system cells could migrate
into the implanted
scaffold, adhere to it, grow and contribute to neural tissue regeneration,» he says.
The staple strands are introduced
into a solution containing the
scaffold strand, and the solution is then heated and cooled.
But in the future, the
scaffold could be inserted
into the body to repair damaged tissue.
The stem cells are supposed to grow over the
scaffold and eventually develop
into a living organ.
The stem cells were supposed to grow
into and over the
scaffold to create a functional trachea.
Macchiarini produced artificial windpipes by taking a polymer
scaffold and «seeding» it with stem cells from the recipient, which he claimed colonized the
scaffold and eventually grew
into a living organ.
Her studies also revealed that BAR domains assemble
into extremely stable
scaffolds on the membrane.