Sentences with phrase «into sickle cell»

Novo Nordisk has moved into sickle cell disease through a licensing deal (PDF) with EpiDestiny.

Finally, the researchers injected these partially differentiated cells into sickle cell mice that had been treated with radiation to kill their own blood stem cells.

Not exact matches

Government funding for research into sickle - cell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds atsickle - cell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds at acell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds atSickle - Cell Society receives no government funds at aCell Society receives no government funds at all).

It occurs when some of the red blood cells change into a «sickle» shape and cause a buildup of red blood cells in small blood vessels.

This elusive stability must be achieved before stem cell supplies can be kept on hand until it is time to turn them into replacements for say misshapen red blood cells seen in sickle cell anemia or abnormal white blood cells causing leukemia.

For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.

Then we corrected the sickle - cell mutations in those cells and injected them back into the diseased mice.

The anti-sickling HSC will be transplanted back into the patient's bone marrow and multiply the corrected cells that make red blood cells without sickling.

Rod Kellems, Ph.D., study co-author and chairman of the Department of Biochemistry and Molecular Biology at the UTHealth Medical School, added, «This research provides insight into how red blood cells work, revealing that SphK1 - mediated elevation of S1P contributes to sickling and promotes disease progression and highlights potential therapeutic opportunities for sickle cell disease.»

Scientists have used the disease - in - a-dish strategy to gain insight into sickle - cell anemia and heart arrhythmias.

In a landmark study that could lead to new therapies for sickle cell anaemia and other blood disorders, UNSW Sydney - led researchers have used CRISPR - gene editing to introduce beneficial natural mutations into blood cells to boost their production of Read more about Solution to 50 - year - old mystery could lead to gene therapy for common blood disorders - Scimex

Stem cell researchers are getting closer to a new treatment for sickle cell disease, moving promising laboratory research into human clinical trials.

One early form of CRISPR - based gene therapy could involve editing the genes responsible for blood disorders like sickle - cell anemia in bone marrow cells, growing them into mature blood cells and injecting them back into patients.

Salk researchers reprogrammed skins cells taken from a sickle cell disease patient into induced pluripotent stem cells (iPSCs), immature cells capable of developing into any type of bodily tissue.

This booklet has been produced based on research into young people with sickle cell disorder in schools in England.

The National Center on Birth Defects and Developmental Disabilities recently translated key sickle cell fact sheets into Spanish and French.