Sentences with phrase «into specific sequences»

Not exact matches

They 3D - print the DNA sequence of a cow and insert it into a specific location of yeast — which they have aptly named Buttercup — obtained from the U.S. Department of Agriculture.

The authors adapted a classical computer science algorithm to combine stable and distinguishing sequence features from individuals» initial microbiome samples into individual - specific «codes.»

Sosa and I pulled on latex gloves and carefully pipetted liquids into tubes to make our guide RNA from scratch — we first synthesized DNA strands with a specific sequence we wanted, used that as a template for the RNA, then destroyed the DNA and isolated the guide RNA from our test tube mixture.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

Densmore envisions a day when you can type such an outcome into a computer, whose algorithms will sift through the databases of known functions and find the specific DNA sequence necessary to achieve such a goal.

It recognizes the specific DNA sequence by inserting a pair of α - helices into grooves of the DNA helix and sensing functional groups on DNA base - pair edges.

«CSPNs represent a new modular drug delivery platform that can be programmed into exquisite structures through sequence - specific fine - tuning of amino acids,» said corresponding author Gaurav Sahay, assistant professor of pharmaceutical sciences at the OSU / OHSU College of Pharmacy.

The students went around Bangalore and into the forests of the state of Karnataka, brought soil samples and looked for BioBrick - specific DNA sequences in the soil microbes.

Molecular recognition (base pairing, i.e., A binds to T and G binds to C) directs the DNA to self - assemble into a specific structure as programed by the staple strand sequences.

After watching the behaviour of many strains, Saxe and colleagues were able to break the communication data into blocks containing specific sequences of calls that occurred repeatedly across different samples.

This requires the development of powerful bioinformatic approaches that allow prediction of haplotypes from numerous variants, and the classification of haplotypes into functionally related categories, in order to identify those specific sequence variants, or combinations of variants, associated with the disease phenotype.

Furthermore, besides offering valuable insight into the function of this novel RNA type, the researchers also believe that the findings will open new avenues for novel treatments in which cell - specific enhancer sequences can be targeted to alter gene expression.

In the presence of an input, ssDNAs (orange curved lines) are produced from a plasmid - borne cassette (gray circles) and recombined into specific genomic loci (orange circles) that are targeted on the basis of sequence homology.

In the presence of a donor DNA molecule with homology to the target region, the CRISPR system can also be used to introduce specific nucleotide modifications into a sequence of interest.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus Erythematosis by utilizing deCODE's expertise in gene discovery.

Constructs lacking the RP sequence were barred from the mitochondria, and even constructs with appended RP were reduced to ~ 13 - 17 % of normal import into mitochondria from mice with a liver - specific, two - thirds reduction in levels of the murine PNPase homolog.

Studying a specific type of genetic variation in the DNA sequences of wolves and domestic dogs - called Single Nucleotide Polymorphisms (SNPs)- the scientists identified the transfer of dog gene variants into wolf genomes.

It was by observation of these sequences that the researchers were able to establish exactly how and at what point the stem cells developed into specific tissue cells and when the silencing occurs.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus...

To positional clone this major sex - specific wing QTL and to more precisely describe its phenotypic effects we (a) reduced the size of the introgressed sequence flanking the ws1 locus to a 40kb segment (see fine - scale mapping and cloning below) and (b) backcrossed the introgressed ws1g segment into a standard N. vitripennis strain (AsymCX) genetic background for > 10 generations.

«Those DNA sequences were put into the mutant; this allows you to test the effect of the gene if it is only switched on in a specific layer.»

Messenger RNA (mRNA) is the specific RNA sequence which is translated into an amino acid sequence that makes up a protein.

This meditation workshop will take you deep into the world of Yoga Nidra by guiding you through a specific sequence of steps to induce a very deep state of relaxation.

Both Harington and Vikander deliver solid performances but Kent can't resist injecting unnecessary soppiness into their relationship with highly stylised sequences and clichés - the heroine longing touching places of her face and body were the hero touched her, close - up shots of a specific part of the love interest's features, etc..

His car, the Chrysler Millennium, wouldn't let him.The car was equipped with a sobriety test: To start the engine, the driver had to punch a certain set of numbers into the car's computer - specific numbers in a specific sequence within a specific amount of time.

In fact, while in that mode, «the page» arguably becomes irrelevant as panels are strung together into one linear sequence, rather than into a series of page - specific sequences.

This essentially places cash payments from multiple mortgages or other debt obligations into a single pool from which specific securities draw in a specific sequence of priority.

Furthering their notion of «sculptural theaters» — installations built as containers for specific movies, whose architectural, audiovisual, and sculptural elements expand onscreen content into environmental panoramas — the artists have transformed Andrea Rosen Gallery into a network of halls and chambers that plot a path for visitors through a sequence of new movies and ambient spaces.

The legal industry doesn't structure its work into activities sequenced in a specific order to produce a service or product for the customer.

• Highly skilled in creating workable and strategic soccer programs aimed at deriving the best from each player • Exceptionally well - versed in providing instructions to players to help them understand game play rules and regulations • Hands - on experience in evaluating performance based on devised metrics and providing suitable feedback • Demonstrated expertise in assessing strengths and weaknesses in each player and identifying areas for development • Effectively able to demonstrate soccer game play by breaking the task down into different sequences • Documented success in inspiring confidence and self - belief in players to ensure that they reach both individual and team goals • Proficient in developing knowledge of fitness, injury, sports psychology and nutrition to make athletes ready for soccer games and practice sessions • Focused on specific areas of soccer such as defensive and offensive play and goalkeeping • Able to develop training sessions for specific plays such as free kicking and corner kicking • Well - versed in choosing / recruiting team members and substitutes for each games, by identifying talent and enthusiasm in individual players • Deep insight into motivating team members and ensuring that the team is following tactics decided and practiced during practice sessions

Then, three years ago, I assembled those handouts, all of which have been tested on thousands of couples, into a book called «A Path for Couples» which describes a specific sequence of skills that couples need.