Sentences with phrase «into synaptic vesicles»

The identification of proteins, VGLUT1 - 3 (Neuron 2001, PNAS 2002), that pump glutamate into synaptic vesicles allows the packaging of the transmitter to be characterised in health and disease (J Comp Neurol 2004, 2006, 2007) and modified by gene knock - out (Science 2004).

While neurotransmitters are created in the interior of the cell, they are pumped, in large quantity, into synaptic vesicles tucked into the wall of a nerve cell's so - called «terminal,» the launch pad from which chemical messages are released from the cell.

Channels, which allow a compound such as glutamate to move from a compartment with high concentrations to one with low concentrations, but not vice versa, can not pump as large amounts of a compound into synaptic vesicles as a transporter can.

To determine whether the protein in question, at the time known as BNPI, mediated the transport of glutamate into synaptic vesicles, the researchers inserted the BNPI DNA into rat cells that normally lacked BNPI protein.

Not exact matches

This allows synaptic vesicles filled with neurotransmitter to fuse with the plasma membrane and release the neurotransmitters into the synaptic cleft.

I ache to see your action potential in action To be blinded by the searing speed of your electric signal As it sparks from node to node To behold the violent beauty of vesicles fusing with your presynaptic membrane — Pouring their contents into your synaptic cleft How I wish to be your postsynaptic cell So that I may be flooded by your molecules

We now know that each quantum, consisting of a collection of around 5000 transmitter molecules, is contained in a little round organelle in the presynaptic terminal that Sanford Palay and George Palade had earlier discovered and called the «synaptic vesicl.e» Neurotransmitter is released from these synaptic vesicles to the outside of the neuron in response to the influx of Ca2 + into the presynaptic terminal.

«Full» vesicles move toward the membrane of the nerve terminal, represented by the overall outline of the figure, where they attach and fuse into the terminal membrane, thereby releasing the transmitter into the space between neurons, the synaptic cleft.

A vesicle is a container made of a lipid membrane from which a neurotransmitter is released into the synaptic cleft — the space between neurons.

«Ultimately this affects the amount of cholesterol that can get into the membranes of the neuron, which form the synapses and the synaptic vesicles — the small structures that contain neurotransmitters.»

During an action potential, calcium influx into the presynaptic terminal triggers the fusion of synaptic vesicles with the plasma membrane, leading to the release of transmitter through the process of exocytosis.