Not exact matches
The cell
into which the
synthetic genome was then transplanted contained its own
proteins, lipids and other molecules.
Synthetic biology enables researchers to tackle a huge and diverse range of applied problems: building a cell with the smallest possible genome; synthesizing
proteins with extra amino acids — more than the 20 found in nature; using bacteria to produce medicines previously too complex to synthesize; even decomposing living organisms
into standard, off - the - shelf «biobricks» that can be assembled on demand.
To understand the underlying technology, it is important to know that these biological sensors consist of
synthetic genes that are read by enzymes and converted
into RNA and
proteins.
The
synthetic molecule blocks these
proteins as they shift from their normal state
into an abnormally folded form by targeting a toxic intermediate phase.
Hartgerink and lead author Vivek Kumar, a postdoctoral researcher at Rice, viewed clotting as a good avenue of investigation for practical application of KOD, a
synthetic protein made of 36 amino acids that self - assemble
into triple - helix nanofibers and hydrogels.
Using their
synthetic D - DapA, the Utah group demonstrated that natural GroEL / ES was capable of folding the D -
protein into its active conformation (i.e., it is «ambidextrous», folding both L - and D -
proteins).
Stretched enough, the
protein molecules snap
into different arrangements, becoming stronger and tougher, and more akin to spider dragline silks and high performance
synthetics like Kevlar, Fudge said.
The
protein threads could be spun and woven
into novel biomaterials, which could provide a sustainable alternative to
synthetic fibres such as Nylon, which are made from petroleum feedstocks.
In 2003, Adrian Krainer and his postdoctoral colleague Luca Cartegni, biochemists at the Cold Sping Harbor Laboratory in New York, engineered a
synthetic, RNA - like molecule that in the test tube changed how the transcripts from SMN2 are spliced
into the mature messenger RNAs that then are translated
into protein — in principle, this could boost production of the normal, full - length SMN
protein.
The team then introduced these
synthetic proteins back
into the cell to see which specific interactions would restore the stem cell's transformative abilities.
By designing
synthetic proteins that can only interact with a pre-determined partner, and introducing them
into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change
into other cell types.
The next step, Chen said, is to build biomimetic membranes by incorporating natural membrane
proteins or other
synthetic water channels such as carbon nanotubes
into these sheet matrices.
mRNAs and
Protein Synthetic Machinery Localize
into Regenerating Spinal Cord Axons When They Are Provided a Substrate That Supports Growth.
The technology included a variety of expression systems, including the wheat germ cell free translation system for eukaryotic gene expression, to take
synthetic gene sequences and translate them
into proteins.
Flavorings, preservatives, sweeteners, emulsifiers and
synthetic nutrients have turned soy
protein isolate, the food processors» ugly duckling,
into a New Age Cinderella.
Also, those studies of the high carb / high
protein diets also need to take
into account high levels of
synthetic folic acid that is added to those refined carbohydrate foods — this is now well known to contribute to cancer and heart disease.
Either
synthetic or naturally occurring
proteins may stimulate the mast cells
into releasing histamine.