Dr. Jain's nominators note that, in sum, his work has provided ``... unprecedented molecular, cellular, anatomical and functional insights
into the vascular pathophysiology of
tumors, for proposing the seminal hypothesis that antiangiogenic therapy can «normalize» the aberrant
vasculature and microenvironment of
tumors and thereby improve both delivery and efficacy of treatment of solid
tumors.»
The scan revealed large adrenal
tumors present on both sides without significant evidence of invasion
into the
vasculature or surrounding structures.