Sentences with phrase «into tumour»

When normal cells turn into tumour cells, some of the antigens on their surface change.

Interference with the entry of nutrients into tumour cells would starve these cells to death.

When injected into the tumour, the gel promotes the kinds of tumour characteristics that immunotherapies can identify.

«This strategy may allow better penetration of larger tumours because the radioisotope can make its way deep into the tumour before releasing the toxic radioactivity trapped inside.»

When a tumour cell is located, the antibody binds to the cell surface and releases the caged radioisotope into the tumour cell.

Cancer arises from the transformation of normal cells into tumour cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumour.

This results in edema in the tissues, which in turn makes it more difficult for drugs to reach into the tumour during cancer therapy.

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumour cells.

«Currently, these can be achieved by means of a direct injection into the tumour or by administering a large dosage of anticancer drugs, which can be painful, expensive, impractical and might have various side effects.»

The specialist in Uro - oncology added that if NTU's technology proves to be viable, clinicians might be able to localise and concentrate the anticancer drugs around a tumour, and introduce the drugs deep into tumour tissues in just a few seconds using a clinical ultrasound system.

A trained robotic surgeon experienced in the treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they need to penetrate into the tumour efficiently in order to reach the cystoplasm of all the cancer cells that are being targeted without affecting the normal cells.

When the sperm hit a solid tumour, the arms sprung open, releasing the sperm and allowing them to swim into the tumour.

This unfortunate and rare side effect of the biopsy provided Nicola Valeri at the Institute of Cancer Research in London and his colleagues with a kind of stopwatch — an exact point in time when a few cells left as the needle was withdrawn began their two year evolution into a tumour.

However, the nanoparticles only released their payload when they reacted with molecules on the tumour's surface, so up to 80 per cent less of the drug needed to be injected to get the same amount into the tumour.

As well as weakening the tumour, which makes it less able to grow and spread to other parts of the body, the drug made blood vessels become more leaky, enabling more chemotherapy drugs to spill into the tumour.

By mixing the gel with a cancer - killing drug and injecting it directly into the tumour, the cancer can be destroyed from the inside.

They then plan to use a retrovirus to introduce the artificial gene into tumour cells.

These were released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

Researchers at the University of Gothenburg are focusing on how HAMLET can be taken up into tumour cells.

Also, why do cancer cells transplanted into healthy organs often not develop into tumours.

Robert Coleman from the University of Sheffield, UK, says we had assumed that bisphosphonates simply wouldn't get into tumours other than bone cancers at any concentration that could make a difference.

Thirty minutes after injecting the gel and cisplatin into the tumours, the levels of cisplatin were five times higher inside the tumour than when the drug was injected without the gel.

Germ cells can develop into tumours — both benign and malignant — particularly in the testes or ovaries, where the cells are normally found.

A new biomarker could help identify abnormal breast cells that will develop into tumours, according to research published in Clinical Cncer Research.

Understanding the processes that restrain mutant cells from developing into tumours, and how they are breached when cancers do form will guide the development of strategies to reduce the chance of cancer development in individuals who have acquired a high level of mutations.

A multi-disciplinary team led by Professor Eleanor Stride won Pioneer Award funding in 2016 to develop a drink containing tiny bubbles of oxygen, which could help to get oxygen back into tumours and boost the effectiveness of cancer treatments.

Not exact matches

Darzalex, however, has not yet reached its peak potential as the drug moves into earlier stages of the disease and is being tested on solid tumours like lung cancer.

The hydra tumour cells were shown to be invasive: if introduced into a healthy organism, they can trigger tumour growth there.

To learn how prostate tumours become drug resistant, researchers led by Michael Karin at the University of California, San Diego, implanted prostate tumours into mice and gave them anti-androgens.

The magnets can sculpt balls into shapes that resemble tumours and tissues growing in the body.

The researchers then injected these tumour - specific cells into mice at the same time as injecting melanoma cells.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

None developed into a malignant tumour.

«Tumour biology needs to be taken into account when deciding adjuvant treatments in this patient population.

The real test will be to inject these cells into mice and see if they form teratomas — tumours containing tissue or structures derived from all three germ layers.

BY a particularly nasty irony, cancers that have been all but eradicated by conventional treatment can often regrow into incurable tumours.

Rodríguez - Perales, Torres and Ramírez have shown that by transferring the RGEN components into primary human cells, regions of the exchanged chromosomes in some tumours can be marked, thus generating cuts in those chromosomes.

To get into the blood vessels, the cell needs to penetrate tissue, both when it leaves the tumour and when it is attaching to a new organ.

One approach would be to identify immune cells in a tumour, grow them in a lab, and then infuse them back into the patient — a technique called adoptive cell transfer.

The innumerable divisions of the bronchi often turn the hunt for tumours in the lungs into a game of chance.

However, occasionally germ cells can get trapped in the wrong part of the body during development and may later turn into brain tumours, for example.

Lois Crandell, the president of Genetronics, says the procedure is painless and can eradicate tumours with doses of toxic drugs 400 times smaller than would be needed if the drugs were injected into the bloodstream.

These cells pick up antigens from tumour cells and «introduce» them to T cells in the lymph nodes, spurring them into action against the tumour.

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour.

«CT perfusion is honing into the change in blood flow to the tumour before and after treatment,» said Ting - Yim Lee, professor at Western University's Schulich School of Medicine & Dentistry, scientist at Lawson Health Research Institute, and a medical physicist at St. Joseph's Health Care London.

In other words, what are the genes that are sending the signal to these lung BMICs to leave the lung tumour, go into the blood stream, invade the blood - brain barrier and form a tumour in the brain.»

The new device will allow for more accurate medical procedures that involve the use of ultrasound to kill tumours, loosen blood clots and deliver drugs into targeted cells.

To carry out the study, the team has analysed how different carbohydrates act on the surface of silver nanoparticles (Ag - NP) of around 50 nanometres, which have been introduced into cultures of liver cells and tumour cells from the nervous system of mice.

Moving forward, the team is looking into ways to assess the feasibility of enhancing RUNX tumour suppression or inhibiting RUNX mitotic function to kill rapidly proliferating cancer cells,» said Prof Ito.

But at the moment we have to use retroviruses to carry the foreign material into the cells, which could generate tumours.