Sentences with phrase «into tumour cells»

When normal cells turn into tumour cells, some of the antigens on their surface change.

Interference with the entry of nutrients into tumour cells would starve these cells to death.

Cancer arises from the transformation of normal cells into tumour cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumour.

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumour cells.

They then plan to use a retrovirus to introduce the artificial gene into tumour cells.

These were released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

Researchers at the University of Gothenburg are focusing on how HAMLET can be taken up into tumour cells.

When a tumour cell is located, the antibody binds to the cell surface and releases the caged radioisotope into the tumour cell.

Not exact matches

Also, why do cancer cells transplanted into healthy organs often not develop into tumours.

The hydra tumour cells were shown to be invasive: if introduced into a healthy organism, they can trigger tumour growth there.

The researchers then injected these tumour - specific cells into mice at the same time as injecting melanoma cells.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

The real test will be to inject these cells into mice and see if they form teratomas — tumours containing tissue or structures derived from all three germ layers.

Rodríguez - Perales, Torres and Ramírez have shown that by transferring the RGEN components into primary human cells, regions of the exchanged chromosomes in some tumours can be marked, thus generating cuts in those chromosomes.

To get into the blood vessels, the cell needs to penetrate tissue, both when it leaves the tumour and when it is attaching to a new organ.

One approach would be to identify immune cells in a tumour, grow them in a lab, and then infuse them back into the patient — a technique called adoptive cell transfer.

Germ cells can develop into tumours — both benign and malignant — particularly in the testes or ovaries, where the cells are normally found.

However, occasionally germ cells can get trapped in the wrong part of the body during development and may later turn into brain tumours, for example.

These cells pick up antigens from tumour cells and «introduce» them to T cells in the lymph nodes, spurring them into action against the tumour.

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour.

The new device will allow for more accurate medical procedures that involve the use of ultrasound to kill tumours, loosen blood clots and deliver drugs into targeted cells.

To carry out the study, the team has analysed how different carbohydrates act on the surface of silver nanoparticles (Ag - NP) of around 50 nanometres, which have been introduced into cultures of liver cells and tumour cells from the nervous system of mice.

Moving forward, the team is looking into ways to assess the feasibility of enhancing RUNX tumour suppression or inhibiting RUNX mitotic function to kill rapidly proliferating cancer cells,» said Prof Ito.

But at the moment we have to use retroviruses to carry the foreign material into the cells, which could generate tumours.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

This is very important for the tumour cells which then spread into the surrounding nervous tissue.

This unfortunate and rare side effect of the biopsy provided Nicola Valeri at the Institute of Cancer Research in London and his colleagues with a kind of stopwatch — an exact point in time when a few cells left as the needle was withdrawn began their two year evolution into a tumour.

Using genetic tools to establish in which cells cancer - driving mutations originated and then propagated into other cancer cells, they demonstrated that a distinct and rare subset of MDS cells showed all the hallmarks of cancer stem cells, and that no other malignant MDS cells were able to propagate the tumour.

A trained robotic surgeon experienced in the treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they need to penetrate into the tumour efficiently in order to reach the cystoplasm of all the cancer cells that are being targeted without affecting the normal cells.

After injecting them into the bloodstream, we are able to gather them around the tumour using magnets and ensure that they don't kill the healthy cells,» explains Asst Prof Xu, who has been working on cancer diagnosis and drug delivery systems since 2004.

Brain cells are often found in ovarian teratomas, but it is extremely unusual for them to organise themselves into brain - like structures, says Masayuki Shintaku at the Shiga Medical Centre for Adults in Japan, who studied the tumour.

But some tumours grow so rapidly their interiors become starved of blood and oxygen, and turn into «necrotic» regions full of dead and dying cells.

When they injected the soil bacterium Clostridium [ck] novyi into the bloodstream of mice with tumours, it spread throughout the necrotic region, consuming living tumour cells as well as dead tissue.

One method is to remove some tumour cells from the patient at the time of surgery, insert a gene for an immune - stimulating protein into them, and return them to the body.

Their studies have shown that, while progenitor cells can give rise to benign lesions, only stem cells have the capacity to develop into deadly invasive tumours.

A new biomarker could help identify abnormal breast cells that will develop into tumours, according to research published in Clinical Cncer Research.

In this film Professor Sir Mike Stratton (director of the Wellcome Trust Sanger Institute) describes how mutations in DNA can cause a cell to grow out of control and develop into a cancerous tumour.

We are investigating how tumour cells can disseminate from the primary tumour and remain alive but clinically undetectable for many years, and how they start expanding into life threatening cancers in some patients.

For analysis of tumour growth over time, 1 × 106 B16F10 luciferase - positive cells were injected s.c. into the right flank of mice.

We initially focused on drilling down into the genetic differences between glioblastoma tumour stem cells and normal neural stem cells.

Understanding the processes that restrain mutant cells from developing into tumours, and how they are breached when cancers do form will guide the development of strategies to reduce the chance of cancer development in individuals who have acquired a high level of mutations.

The DNA from cancer cells is mutated and this mutated DNA can get into the blood stream (circulating tumour DNA, ctDNA) and be detected by sequencing the DNA in blood.

Here Steve tells us how his interest in stem cells led him into cancer research and how he believes this angle of brain tumour research has unique potential for tackling cancers which are currently difficult to treat.

Steve tells us how his interest in stem cells led him into cancer research, and the potential for breakthroughs in brain tumour research and treatment.