Not exact matches
However, to be truly useful, one must be able to transplant the bacterial
chromosome from
yeast back
into a recipient bacterial cell.
Finally, the team inserted these quarters
into yeast, which copied and combined them
into a complete
chromosome.
With the edits made, the team starts to assemble edited, synthetic DNA sequences
into ever larger chunks, which are finally introduced
into yeast cells, where cellular machinery finishes building the
chromosome.
Szostak knew that non-chromosomal linear DNAs in
yeast normally insert themselves
into chromosomes or are destroyed by cellular enzymes, presumably because they behave as if they result from random fractures.