Sentences with phrase «into yeast prions»

Study coauthor Susan Lindquist of the Whitehead Institute for Biomedical Research in Cambridge, Mass., and her colleagues devised a way to test plant proteins for prion power by swapping bits of them into yeast prions.

Not exact matches

(stock image) Whitehead Institute scientists inserted the Arabidopsis thaliana protein Luminidependens (LD) into yeast to determine whether it has the traits of a prion.

To see if the candidates have the properties of prions, the scientists inserted the proteins into yeast, a model that the Lindquist lab has studied extensively.

Moreover, when the protein snippet was inserted into yeast, it could replace the functions of a known prion - forming yeast protein.

Yeast can also carry prions, and the duo fused part of a yeast prion protein called Sup35 to a normal rat protein that controls the transcription of DNA intoYeast can also carry prions, and the duo fused part of a yeast prion protein called Sup35 to a normal rat protein that controls the transcription of DNA intoyeast prion protein called Sup35 to a normal rat protein that controls the transcription of DNA into RNA.

Meanwhile, Eisenberg and his group zoomed in on a yeast prion, discovering that it had interlocking teeth like a zipper, which contorted the proteins into a ropelike shape.

Previously, True and Whitehead Institute Director Susan Lindquist reported that a particular yeast protein called Sup35 somehow altered the metabolic properties — or phenotype — of the cell when it «misfolded» into a prion state.

Mounting evidence has linked Hsp 104 to a role in regulating whether the yeast prion folds into its normal working or abnormal non-functional conformation.