Sentences with phrase «intracellular domain»
The phrase "intracellular domain" refers to a specific part or region of a cell. It represents the area within the cell, which is surrounded by its membrane. This domain plays a vital role in various cellular processes, including signal transduction, protein interactions, and controlling cell behavior. It serves as a hub for receiving and transmitting signals, allowing the cell to communicate with its environment and coordinate its activities effectively. Full definition
Poolman: «For example, we noticed that membrane proteins with large intracellular domains can not enter them.»
sciencedaily.com
intracellular domains are genetically engineered to target PDPN, a protein usually found in abundance in solid tumors, including GBM, which presents the worst prognosis among GBM subtypes.
They propose that the banana - shaped proteins on the inner side of the membrane get in the way of the intracellular domains, which hinders their diffusion into the eisosomes.
Overexpression of Jagged - 1 and its intracellular domain in human mesenchymal stromal cells differentially affect the interaction with hematopoietic stem and progenitor cells.
Duryagina R, Thieme S, Anastassiadis K, Werner C, Schneider S, Wobus M, Brenner S, Bornhäuser M Overexpression of Jagged - 1 and its intracellular domain in human mesenchymal stromal cells differentially affect the interaction with hematopoietic stem and progenitor cells.
A direct positive feedback loop, in which the intracellular domain of activated Notch receptors binds to an enhancer in the second intron of the Notch1 gene to enhance its expression, is critical for intestinal stem cell self ‐ renewal and niche patterning.