The resulting drop in glutathione production and
intracellular glutathione concentrations compromises the mitochondria's ability to scavenge reactive oxygen species (ROS), producing a vicious cycle that drives the progressive increase in ROS - mediated structural damage and its corollary, the progressive decline in energy production and repair that accompanies aging.
Not exact matches
«[Immunocal is]... a U.S. patented natural food protein concentrate in the FDA category of GRAS (generally recognized as safe) which assists the body in maintaining optimal
concentrations of
glutathione (GSH) by supplying the precursors required for
intracellular glutathione synthesis.
This causes a decrease in
intracellular glutathione (GSH) and a corresponding increase in ROS (H2O2, O2 --RRB-
concentrations that further upregulates the insulin - independent insulin receptor signaling, perpetuating the cycle.