Sentences with phrase «intracellular signaling molecule»

CRAC channels control the entry of calcium into immune and other cell types, and calcium is an important intracellular signaling molecule that modulates cytokine production and the immune response.

Some of Professor Graybiel's more recent work has centered on findings that certain intracellular signalling molecules are more highly expressed in parts of the striatum of mice and rats during the learning of new habits.

Not exact matches

Several target molecules have also been identified in intracellular signalling pathways and in cell survival proteins.

Biology is rife with examples of modularity: the overwhelming majority of molecules in a cell is either part of an intracellular complex with modular activity, such as the ribosome, or participates in an extended (functional) module as a temporally regulated element of a relatively distinct process (e.g., signal amplification in a phosphorylation ‐ mediated signaling pathway).

Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class of cell surface proteins that function in the interactions of immune cells with other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune disease.

Molecules in the extracellular environment bind specifically to cell - surface receptors and trigger intracellular signaling, eventually leading to changes in cellular physiology.

Intracellular levels of NAD + regulate immune and inflammatory pathways, including the cytokine TNF - alpha, a critical signaling molecule.34, 35